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BBC3 Polyclonal Antibody

BBC3 Polyclonal Antibody

Item no.	E-AB-40332-120
Manufacturer	Elabscience
Amount	120 uL
Quantity options	100 uL 120 uL 20 uL 200 uL 25 uL 60 uL
Category	Oncology Antibodies By Cell Type Blastoma Carcinoma Glioma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma Cell Biology Cell Status Apoptosis Adenocarcinoma Immunohistochemistry Autophagy Cardiovascular Research Ischemia & Reperfusion Injury Primary Antibodies Astrocytoma By Organ Colorectal Cancer Breast Cancer Testicular & Prostate Cancer
Type	Antibody Polyclonal
Applications	WB, IHC
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	BBC 3, Bbc3, BBC3, BCL 2 binding component 3, Bcl-2-binding component 3, BCL2 binding component 3, JFY 1, JFY-1, JFY1, p53 up regulated modulator of apoptosis, p53 up-regulated modulator of apoptosis, p53 Upregulated Modulator of Apoptosis, PUMA alpha, PUMA/JFY1
Similar products	BBC3, Bcl-2-binding component 3, JFY-1, p53 up-regulated modulator of apoptosis, Bbc3, JFY1, PUMA/JFY1, BCL2 binding component 3, BBC 3, BCL 2 binding component 3, JFY 1, p53 up regulated modulator of apoptosis, p53 Upregulated Modulator of Apoptosis, PUMA alpha
Shipping Condition	Cool pack
Hazard information	Comply with cargo safety certificate
Available
Manufacturer - Category	Primary Antibodies
Manufacturer - Targets	BBC3
Shipping Temperature	The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions	Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight	21kDa
Observed Molecular Weight	26kDa
Manufacturer - Research Areas	Cancer, Cell Biology, Metabolism, Signal Transduction
Background	This gene encodes a member of the BCL-2 family of proteins. This family member belongs to the BH3-only pro-apoptotic subclass. The protein cooperates with direct activator proteins to induce mitochondrial outer membrane permeabilization and apoptosis. It can bind to anti-apoptotic Bcl-2 family members to induce mitochondrial dysfunction and caspase activation. Because of its pro-apoptotic role, this gene is a potential drug target for cancer therapy and for tissue injury. Alternative splicing results in multiple transcript variants.
Concentration	1 mg/mL
Buffer	PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4
Purification Method	Antigen Affinity Purification
Recommended Dilution	WB 1:500-1000; IHC 1:100-1:200
Abbreviation	BBC3
Clonality	Polyclonal
Immunogen	Recombinant Human Bcl-2-binding component 3 protein
Category ID III	Polyclonal Antibodies

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.