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Phospho-DDR1 (Tyr513) Polyclonal Antibody

Phospho-DDR1 (Tyr513) Polyclonal Antibody

Item no.	E-AB-51058-200
Manufacturer	Elabscience
Amount	200 uL
Quantity options	120 uL 20 uL 200 uL 60 uL
Category	Oncology Neuroscience Neural Lineage Markers Molecular Targets for Neuroscience Neural Signaling Protein Aggregation, Clearance & Misfolding Neural Adhesion Molecules Antibodies By Cell Type Blastoma Carcinoma Glioma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma Western Blot ELISA Primary Antibodies Astrocytoma By Organ Colorectal Cancer Heart & Blood Cancer Thyroid Cancer Calcium Binding Protein Markers Interneuron Markers
Type	Antibody Polyclonal
Applications	WB
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	CAK, CD 167, CD167, CD167 antigen-like family member A, CD167a, Cell adhesion kinase, DDR 1, DDR, DDR1, DDR1, Discoidin domain receptor, Discoidin domain receptor tyrosine kinase 1, Discoidin receptor tyrosine kinase, Discoidin receptor tyrosine kinase isoform a, EDDR 1, EDDR1, Epithelial discoidin domain receptor 1, Epithelial discoidin domain-containing receptor 1, Epithelial specific receptor kinase, HGK2, Mammarian carcinoma kinase 10, Mammary carcinoma kinase 10, MCK-10, MCK10, NEP, Neuroepithelial tyrosine kinase, Neurotrophic tyrosine kinase receptor type 4, NTRK 4, NTRK4, OTTHUMP00000029343, OTTHUMP00000029344, OTTHUMP00000029345, OTTHUMP00000029346, OTTHUMP00000029347, OTTHUMP00000164863, OTTHUMP00000164867, OTTHUMP00000222080, Protein-tyrosine kinase 3A, Protein-tyrosine kinase RTK-6, PTK 3, PTK 3A protein tyrosine kinase 3A, PTK3, PTK3A, Receptor tyrosine kinase NEP, RTK 6, RTK6, TRK E, TRKE, Tyrosine kinase DDR, Tyrosine kinase receptor E, Tyrosine-protein kinase CAK
Similar products	DDR1, CD167a, CAK, EDDR1, NEP, NTRK4, PTK3A, RTK6, TRKE, Epithelial discoidin domain-containing receptor 1, CD167 antigen-like family member A, Cell adhesion kinase, Discoidin receptor tyrosine kinase, HGK2, Mammary carcinoma kinase 10, Protein-tyrosine kinase 3A, MCK10, CD167, DDR, PTK3, OTTHUMP00000029344, OTTHUMP00000029345, OTTHUMP00000029346, OTTHUMP00000029347, Discoidin domain receptor, CD 167, DDR 1, Discoidin receptor tyrosine kinase isoform a, EDDR 1, Epithelial discoidin domain receptor 1, Mammarian carcinoma kinase 10, Neuroepithelial tyrosine kinase, Neurotrophic tyrosine kinase receptor type 4, NTRK 4, PTK 3, PTK 3A protein tyrosine kinase 3A
Shipping Condition	Cool pack
Hazard information	Comply with cargo safety certificate
Available
Manufacturer - Category	Primary Antibodies
Manufacturer - Targets	DDR1 (Phospho-Tyr513) Antibody
Shipping Temperature	The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions	Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Observed Molecular Weight	130kDa
Research Areas	Cancer, Cardiovascular, Neuroscience, Signal Transduction
Background	Receptor tyrosine kinases play a key role in the communication of cells with their microenvironment. These kinases are involved in the regulation of cell growth, differentiation and metabolism. The protein encoded by this gene belongs to a subfamily of tyrosine kinase receptors with homology to Dictyostelium discoideum protein discoidin I in their extracellular domain, and that are activated by various types of collagen. Expression of this protein is restricted to epithelial cells, particularly in the kidney, lung, gastrointestinal tract, and brain. In addition, it has been shown to be significantly overexpressed in several human tumors. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. DDR1 (Discoidin Domain Receptor Tyrosine Kinase 1) is a Protein Coding gene. Diseases associated with DDR1 include Pulmonary Fibrosis, Idiopathic and Breast Cancer. Among its related pathways are GPCR Pathway and Nanog in Mammalian ESC Pluripotency. GO annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is DDR2.
Concentration	1 mg/mL
Buffer	PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Purification Method	Affinity purification
Recommended Dilution	WB 1:500-2000
Abbreviation	DDR1 (Phospho-Tyr513) Antibody
Clonality	Polyclonal
Immunogen	Synthesized phospho derived from human DDR1 (Phospho-Tyr513)
Category ID III	Acetyl/Phospho/Methyl Antibodies

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

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