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MCM10 Polyclonal Antibody

MCM10 Polyclonal Antibody

Item no.	E-AB-52160-20
Manufacturer	Elabscience
Amount	20 uL
Quantity options	120 uL 20 uL 200 uL 60 uL
Category	Antibodies Cell Biology Cell Status Immunohistochemistry ELISA Proliferation Primary Antibodies
Type	Antibody Polyclonal
Applications	IHC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Minichromosome Maintenance 10 Replication Initiation Factor, Minichromosome Maintenance Complex Component 10, Protein MCM10 Homolog, HsMCM10, MCM10 Minichromosome Maintenance Deficient 10 , Homolog Of Yeast MCM10, PRO2249, CNA43, DNA43
Similar products	CNA43, DNA43, PRO2249, Minichromosome Maintenance Complex Component 10, Minichromosome Maintenance 10 Replication Initiation Factor, Protein MCM10 Homolog, HsMCM10, MCM10 Minichromosome Maintenance Deficient 10, Homolog Of Yeast MCM10
Shipping Condition	Cool pack
Hazard information	Comply with cargo safety certificate
Available
Manufacturer - Category	Primary Antibodies
Manufacturer - Targets	MCM10
Shipping Temperature	The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions	Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Manufacturer - Research Areas	The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the
Background	The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre-RC) and it may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein can interact with MCM2 and MCM6, as well as with the origin recognition protein ORC2. It is regulated by proteolysis and phosphorylation in a cell cycle-dependent manner. Studies of a similar protein in Xenopus suggest that the chromatin binding of this protein at the onset of DNA replication is after pre-RC assembly and before origin unwinding. Alternatively spliced transcript variants encoding distinct isoforms have been identified.
Concentration	0.7 mg/mL
Buffer	PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Purification Method	Antigen affinity purification
Recommended Dilution	IHC 1:35-1:200
Abbreviation	MCM10
Clonality	Polyclonal
Immunogen	Fusion protein of human MCM10
Category ID III	Polyclonal Antibodies

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