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LIG4 Polyclonal Antibody

LIG4 Polyclonal Antibody

Item no.	E-AB-52776-120
Manufacturer	Elabscience
Amount	120 uL
Quantity options	120 uL 20 uL 200 uL 60 uL
Category	Oncology Metabolism Cholesterol & Lipid Metabolism Antibodies By Cell Type Melanoma Immunohistochemistry ELISA Enzymes Prostaglandin Synthases Primary Antibodies
Type	Antibody Polyclonal
Applications	IHC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	DNA ligase IV ATP dependent, DNA joinase, DNA ligase 4, DNA ligase IV, DNA repair enzyme, DNLI4, LIG 4, LIG4, LIG4S, Ligase IV, Ligase IV DNA ATP dependent, Polydeoxyribonucleotide synthase [ATP] 4, Polydeoxyribonucleotide synthase 4, Polydeoxyribonucleotide synthase, Polynucleotide ligase, Sealase
Similar products	LIG4, DNA joinase, DNA repair enzyme, DNLI4, Polydeoxyribonucleotide synthase, DNA ligase IV ATP dependent, DNA ligase 4, DNA ligase IV, LIG 4, Ligase IV, Ligase IV DNA ATP dependent, Polydeoxyribonucleotide synthase [ATP] 4, Polydeoxyribonucleotide synthase 4, Polynucleotide ligase, LIG4S, Sealase
Shipping Condition	Cool pack
Hazard information	Comply with cargo safety certificate
Available
Manufacturer - Category	Primary Antibodies
Manufacturer - Targets	LIG4
Shipping Temperature	The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions	Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Manufacturer - Research Areas	Cancer, Epigenetics and Nuclear Signaling
Background	The protein encoded by this gene is a DNA ligase that joins single-strand breaks in a double-stranded polydeoxynucleotide in an ATP-dependent reaction. This protein is essential for V(D)J recombination and DNA double-strand break (DSB) repair through nonhomologous end joining (NHEJ). This protein forms a complex with the X-ray repair cross complementing protein 4 (XRCC4), and further interacts with the DNA-dependent protein kinase (DNA-PK). Both XRCC4 and DNA-PK are known to be required for NHEJ. The crystal structure of the complex formed by this protein and XRCC4 has been resolved. Defects in this gene are the cause of LIG4 syndrome. Alternatively spliced transcript variants encoding the same protein have been observed.
Concentration	1.08 mg/mL
Buffer	PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Purification Method	Antigen affinity purification
Recommended Dilution	IHC 1:50-1:300
Abbreviation	LIG4
Clonality	Polyclonal
Immunogen	Fusion protein of human LIG4
Category ID III	Polyclonal Antibodies

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.