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PGC1 alpha Polyclonal Antibody

PGC1 alpha Polyclonal Antibody

Item no.	E-AB-65852-120
Manufacturer	Elabscience
Amount	120 uL
Quantity options	120 uL 200 uL 60 uL
Category	Oncology Metabolism Glucose Homeostasis Antibodies Western Blot Immunofluorescence Primary Antibodies By Organ Thyroid Cancer
Type	Antibody
Applications	WB, IF
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
Citations	https://www.sciencedirect.com/science/article/pii/S0024320522009584 / https://onlinelibrary.wiley.com/doi/abs/10.1096/fj.201901510RR / https://www.sciencedirect.com/science/article/pii/S0024320522003496
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	PPARGC1A, LEM6, PGC-1(alpha), PGC-1alpha, PGC-1v, PGC1, PGC1A, PPARGC1, PPARG coactivator 1 alpha, PGC1 alpha
Shipping Condition	Cool pack
Available
Manufacturer - Category	Primary Antibodies
Shipping Temperature	The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions	Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight	14kDa/30kDa/31kDa/33kDa/77kDa/89kDa/91kDa
Observed Molecular Weight	110kDa
Research Areas	Cancer, Cardiovascular, Epigenetics and Nuclear Signaling, Metabolism
Background	The protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of, cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination. This protein may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, and the development of obesity.
Concentration	1mg/mL
Buffer	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification Method	Affinity purification
Recommended Dilution	WB 1:500-1:2000; IF 1:50-1:200
Abbreviation	PGC1 alpha
Clonality	Polyclonal
Immunogen	A synthetic peptide of human PGC1 alpha (NP_037393.1).

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.