MBP Polyclonal Antibody

MBP

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

17-22kDa

MBP belongs to the myelin basic protein family. The classic group of MBP isoforms (isoform 4-isoform 14) are the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non-classic group of MBP isoforms (isoform 1-isoform 3/Golli-MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T-cells and neural cells. MBP has six isoforms. Catalog#10458-1-AP is capable of recognizing multiple isoforms of MBP.

PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4

WB 1:500-1:1000; IHC 1:200-1:600

Polyclonal

Polyclonal Antibodies