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CD284 Polyclonal Antibody

CD284 Polyclonal Antibody

Item no.	E-AB-70375-200
Manufacturer	Elabscience
Amount	200 uL
Quantity options	120 uL 200 uL 60 uL
Category	Neuroscience Neural Lineage Markers Metabolism Diabetes Glucose Homeostasis Antibodies Obesity Immunohistochemistry Western Blot Primary Antibodies
Type	Antibody Polyclonal
Applications	WB, IHC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
Citations	https://www.sciencedirect.com/science/article/pii/S0024320521008626 https://academic.oup.com/jpp/article-abstract/73/4/473/6118677
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	ARMD10, CD284, CD284 antigen, Homolog of Drosophila toll, hToll, TLR 4, TLR4, TLR4, TOLL, Toll like receptor 4, Toll-like receptor 4
Similar products	TLR4, Toll-like receptor 4, ARMD10, CD284, TOLL, hToll, CD284 antigen, Homolog of Drosophila toll, TLR 4, Toll like receptor 4
Shipping Condition	Cool pack
Hazard information	Comply with cargo safety certificate
Available
Manufacturer - Category	Primary Antibodies
Manufacturer - Targets	CD284
Shipping Temperature	The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions	Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight	95kDa
Observed Molecular Weight	95kDa
Manufacturer - Research Areas	Cancer, Cardiovascular, Immunology, Microbiology
Background	TLR4, also named as CD284, belongs to the Toll-like receptor family. TLR4 cooperates with LY96 and CD14 to mediates the innate immune response to bacterial lipopolysaccharide (LPS). TLR4 acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Three alternatively spliced transcript variants that encode different protein isoforms have been described.
Concentration	0.9 mg/mL
Buffer	PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4
Purification Method	Affinity purification
Recommended Dilution	WB 1:500-1:2000; IHC 1:500-1:2000
Abbreviation	CD284
Clonality	Polyclonal
Immunogen	KLH conjugated Synthetic peptide corresponding to Mouse TLR4.
Category ID III	Polyclonal Antibodies

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.