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Purified Anti-Mouse CD86 Antibody[GL-1]

Purified Anti-Mouse CD86 Antibody[GL-1]

Item no.	E-AB-F0994A-25
Manufacturer	Elabscience
Amount	25 ug
Quantity options	100 ug 1 mg 25 ug 50 ug 5 mg
Category	Antibodies Primary Antibodies
Type	Antibody Monoclonal
Applications	FC
Clone	GL-1
Specific against	Mouse (Murine, Mus musculus)
Host	Rat
Isotype	IgG2a Kappa
Conjugate/Tag	Unconjugated
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	T-lymphocyte activation antigen CD86, Cd86, Activation B7-2 antigen, Early T-cell costimulatory molecule 1, ETC-1,
Shipping Condition	Cool pack
Available
Manufacturer - Category	Flow Cytometry Antibodies
Manufacturer - Isotype	Rat IgG2a, κ
Shipping Temperature	Ice bag
Storage Conditions	Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
Background	CD86 is an 80 kD immunoglobulin superfamily member also known as B7-2, B70, and Ly-58. CD86 is expressed on activated B and T cells, macrophages, dendritic cells, and astrocytes. CD86, along with CD80, is a ligand of CD28 and CD152 (CTLA-4). CD86 is expressed earlier in the immune response than CD80. CD86 has also been shown to be involved in immunoglobulin class-switching and triggering of NK cell-mediated cytotoxicity. CD86 binds to CD28 to transduce co-stimulatory signals for T cell activation, proliferation, and cytokine production. CD86 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.
Concentration	≥1 mg/mL
Buffer	Phosphate buffered solution, pH 7.2, containing 0.05% proclin 300.
Abbreviation	CD86
Clonality	Monoclonal
Usage	Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 10^6 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.