Elab Fluor® 488 Anti-Mouse CD122/IL-2RB Antibody[5H4]

Primary Antibodies

CD122; IL-2RB

This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

CD122 is a 70-75 kD IL-2 receptor β chain also known as IL-2Rβ, which is also shared by the IL-15 receptor. It is constitutively expressed by NK cells and at lower levels by T cells, B cells, monocytes, and macrophages. The IL-2Rβ chain can combine with either the common γ subunit (γc, CD132) alone or with the γc subunit and the IL-2Rα subunit (CD25) to generate intermediate or high affinity IL-2 receptor complexes, respectively. CD122 expression levels can be upregulated by activation. The 5H4 antibody does not block IL-2 binding to the IL-2 receptor. CD122 is expressed on murine, but not human, CD8+ Tregs involved in the maintenance of T cell homeostasis.

Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

Monoclonal

Flow Cytometry Antibodies