« Back
Home /
PE/Cyanine5.5 Anti-Mouse CD45R/B220 Antibody[RA3.3A 1/6.1]

PE/Cyanine5.5 Anti-Mouse CD45R/B220 Antibody[RA3.3A 1/6.1]

Item no.	E-AB-F1112I-200
Manufacturer	Elabscience
Amount	100 T x 2
Quantity options	100 T 20 T 100 T x 2 50 T 500 T
Category	Antibodies Primary Antibodies
Type	Antibody Monoclonal
Applications	FC
Clone	RA3.3A 1/6.1
Specific against	Mouse (Murine, Mus musculus)
Host	Rat
Isotype	IgM Kappa
Conjugate/Tag	Cy5.5, PE
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	B220
Shipping Condition	Cool pack
Available
Manufacturer - Category	Primary Antibodies / Flow Cytometry Antibodies
Manufacturer - Isotype	Rat IgM, κ
Shipping Temperature	Ice bag
Storage Conditions	This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Research Areas	Cell Biology, Immunology, Inhibitory Molecules, Neuroscience, Neuroscience Cell Markers
Background	CD45R, also known as B220, is an isoform of CD45. It is a member of the protein tyrosine phosphatase (PTP) family with a molecular weight of approximately 180-240 kD. CD45R is expressed on B cells (at all developmental stages from pro-B cells through mature B cells), activated B cells, and subsets of T and NK cells. CD45R (B220) is also expressed on a subset of abnormal T cells involved in the pathogenesis of systemic autoimmunity in MRL-Fas^lpr and MRL-Fas^gld mice. It plays a critical role in TCR and BCR signaling. The primary ligands for CD45 are galectin-1, CD2, CD3, and CD4. CD45R is commonly used as a pan-B cell marker; however, CD19 may be more appropriate for B cell specificity.
Concentration	5 μL/Test
Buffer	Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Abbreviation	CD45R; B220
Clonality	Monoclonal
Usage	Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.