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APC Anti-Human CD45 Antibody[HI30]

APC Anti-Human CD45 Antibody[HI30]

Item no.	E-AB-F1137E-200
Manufacturer	Elabscience
Amount	100 Tests x 2
Quantity options	100 T 20 T 100 Tests x 2 50 T
Category	Oncology Neuroscience Neural Lineage Markers Metabolism Diabetes Antibodies By Cell Type Carcinoma Hematology Leukemia Flow Cytometry Primary Antibodies Progenitor Markers
Type	Antibody Monoclonal
Applications	FC
Clone	HI30
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG1 Kappa
Conjugate/Tag	APC
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	CD45, L-CA, Ly-5, Ptprc, Receptor-type tyrosine-protein phosphatase C, T200
Similar products	CD45, Ptprc, L-CA, T200, Receptor-type tyrosine-protein phosphatase C, Ly-5
Shipping Condition	Cool pack
Hazard information	Comply with cargo safety certificate
Available
Manufacturer - Applications	FCM
Manufacturer - Category	Primary Antibodies
Manufacturer - Isotype	Mouse IgG1, κ
Manufacturer - Targets	CD45
Shipping Temperature	Ice bag
Storage Conditions	This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Research Areas	Cell Biology, Immunology, Inhibitory Molecules, Innate Immunity, Neuroscience, Neuroscience Cell Markers, Stem Cells
Background	CD45 is a 180 - 240 kD single chain type I membrane glycoprotein also known as leukocyte common antigen (LCA) and T200. It is a tyrosine phosphatase expressed on the plasma membrane of all hematopoietic cells, except erythrocytes or platelets. CD45 is a signaling molecule that regulates a variety of cellular processes including cell growth, differentiation, cell cycle, and oncogenic transformation. CD45 plays a critical role in T and B cell antigen receptor-mediated activation by dephosphorylating substrates including p56Lck, p59Fyn, and other Src family kinases. CD45 non-covalently associates with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to bind galectin-1 and to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4.
Concentration	5 μL/Test
Buffer	Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Abbreviation	CD45
Clonality	Monoclonal
Usage	Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Category ID III	Flow Cytometry Antibodies

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.