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PE/Elab Fluor® 594 Anti-Human CD45 Antibody[HI30]

PE/Elab Fluor® 594 Anti-Human CD45 Antibody[HI30]

Item no.	E-AB-F1137P-50
Manufacturer	Elabscience
Amount	50 T
Quantity options	100 T 20 T 100 T x 2 50 T
Category	Oncology Neuroscience Neural Lineage Markers Metabolism Diabetes Antibodies By Cell Type Carcinoma Hematology Leukemia Flow Cytometry Primary Antibodies Progenitor Markers
Type	Antibody
Applications	FC
Clone	HI30
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG1 Kappa
Conjugate/Tag	Elab Fluor 594, PE
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	CD45, L-CA, Ly-5, Ptprc, Receptor-type tyrosine-protein phosphatase C, T200
Shipping Condition	Cool pack
Available
Manufacturer - Category	Primary Antibodies / Flow Cytometry Antibodies
Manufacturer - Isotype	Mouse IgG1, κ
Shipping Temperature	Ice bag
Storage Conditions	This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Research Areas	Cell Biology, Immunology, Inhibitory Molecules, Innate Immunity, Neuroscience, Neuroscience Cell Markers, Stem Cells
Background	CD45 is a 180 - 240 kD single chain type I membrane glycoprotein also known as leukocyte common antigen (LCA) and T200. It is a tyrosine phosphatase expressed on the plasma membrane of all hematopoietic cells, except erythrocytes or platelets. CD45 is a signaling molecule that regulates a variety of cellular processes including cell growth, differentiation, cell cycle, and oncogenic transformation. CD45 plays a critical role in T and B cell antigen receptor-mediated activation by dephosphorylating substrates including p56Lck, p59Fyn, and other Src family kinases. CD45 non-covalently associates with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to bind galectin-1 and to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4.
Concentration	5 μL/Test
Buffer	Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Abbreviation	CD45
Clonality	Monoclonal
Usage	Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.