APC Anti-Human IL-21 Antibody[3A3-N2]

Primary Antibodies

IL-21

This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Interleukin 21 (IL-21) is a potent immunomodulatory cytokine mainly produced by NKT and CD4+ T-cells, particularly the inflammatory Th17 subset, and has pleiotropic effects on both innate and adaptive immune responses. These actions include positive effects such as enhancing proliferation of NK cells and cytotoxic T cells, and inhibitory effects on the antigen-presenting function of dendritic cells. It can also be proapoptotic for B cells and NK cells. Studies have shown that IL-21 is also an autocrine cytokine that potently induces Th17 differentiation, suppresses Foxp3 expression, and serves as a target for treating inflammatory diseases.

Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

Monoclonal

Flow Cytometry Antibodies