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APC Anti-Mouse CD105 Antibody[MJ7/18]

APC Anti-Mouse CD105 Antibody[MJ7/18]

Item no.	E-AB-F1233E-200
Manufacturer	Elabscience
Amount	100 T x 2
Quantity options	100 T 20 T 100 T x 2 50 T
Category	Oncology Neuroscience Neuroinflammation Molecular Targets for Neuroscience Neural Development Antibodies By Cell Type Carcinoma Hematology Leukemia Lymphoma Myeloma Melanoma Flow Cytometry Primary Antibodies
Type	Antibody
Applications	FC
Clone	MJ7/18
Specific against	Mouse (Murine, Mus musculus)
Host	Rat
Isotype	IgG2a Kappa
Conjugate/Tag	APC
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	END, Endoglin, Eng
Shipping Condition	Cool pack
Available
Manufacturer - Category	Primary Antibodies / Flow Cytometry Antibodies
Manufacturer - Isotype	Rat IgG2a, κ
Shipping Temperature	Ice bag
Storage Conditions	This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Research Areas	Angiogenesis, Cell Adhesion, Cell Biology, Immunology, Stem Cells
Background	CD105 is a 90 kD homodimeric type I integral membrane glycoprotein, also known as endoglin. It is expressed on endothelial cells (especially on angiogenic endothelial cells) and upregulated by hypoxia, activated monocytes, macrophages, bone marrow stromal cells, and some cytotrophoblasts. CD105 is a receptor for TGF-β1, TGF-β3 and modulates TGF-β signaling by interacting with TGF-β receptors I and/or II. CD105 also binds other growth factors such as actvin A, BMP-2, and BMP-7. CD105 has been show to be a useful marker for identifying proliferating endothelium involved in tumor angiogenesis and can be used for tumor imaging and prognosis, and has therapeutic potential for some solid tumors and other angiogenic diseases.
Concentration	5 μL/Test
Buffer	Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Abbreviation	CD105
Clonality	Monoclonal
Usage	Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.