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APLF Antibody

APLF Antibody

Item no.	E18-0108-1
Manufacturer	Enogene
Amount	50 ug/50 ul
Quantity options	100 ug/100 ul 50 ug/50 ul 100 ug/100 ul 100 ug
Category	Antibodies Immunohistochemistry Western Blot Primary Antibodies
Type	Antibody
Applications	WB, IHC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	APFL, APLF, Aprataxin and PNK-like factor, aprataxin and PNKP like factor, aprataxin- and PNK-like factor, Apurinic-apyrimidinic endonuclease APLF, C2orf13, FLJ16593, MGC47799, PALF, PNK and APTX-like FHA domain-containing protein, PNK and APTX-like FHA p
Available
Specificity	APLF antibody detects endogenous levels of total APLF
Manufacturer - Applications	WB: 1:500~1:3000 IHC: 1:50~1:200
Manufacturer - Conjugate / Tag	This antibody is also available with the following conjugates: AF350, AF405L, AF405M, AF405S, AF488, AF514, AF532, AF546, AF555, AF568, AF594, AF610, AF635, AF647, AF680, AF700, AF750, AF790, APC, AP, Biotin, Cy3, Cy5.5, Cy5, Cy7, FITC, HRP, PE, Magnetic beads (1 um, 2.8 um, 3 um, 4.5 um, 5 um, 10 um, 15 um, 20 um, 30 um, or different size option) Please contact sales@hoelzel.de for pricing and availability.
Storage Conditions	Store at -20C/1 year
Molecular Weight	57kDa
Immunogen	A synthesized peptide derived from human APLF
Purification	Affinity-chromatography
Background	APLF Nuclease involved in single-strand and double-strand DNA break repair. Recruited to sites of DNA damage through interaction with poly(ADP-ribose), a polymeric post-translational modification synthesized transiently at sites of chromosomal damage to accelerate DNA strand break repair reactions. Displays apurinic- apyrimidinic (AP) endonuclease and 3'-5' exonuclease activities in vitro. Also able to introduce nicks at hydroxyuracil and other types of pyrimidine base damage. Belongs to the APLF family. Interacts with LIG4, PARP1, XRCC1, XRCC4 and XRCC5.
Formulation Description	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 C.Stable for 12 months from date of receipt
CiteID	EN0035298

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 ug/50 ul

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Delivery expected until 9/25/2025

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