Comparison

anti- ARHGEF5 antibody

Manufacturer FineTest
Category
Type Antibody Monoclonal
Specific against Human, Mouse, Rat
Isotype IgG
Format liquid
Amount 100ug
Host Rabbit
Item no. FNab00563-100ug
eClass 6.1 32160702
eClass 9.0 42030590
Available
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Clonality
polyclonal
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20C for 12 months(Avoid repeated freeze / thaw cycles.)
Background
Guanine nucleotide exchange factor which activates Rho GTPases(PubMed:15601624). Strongly activates RHOA(PubMed:15601624). Also strongly activates RHOB, weakly activates RHOC and RHOG and shows no effect on RHOD, RHOV, RHOQ or RAC1(By similarity). Involved in regulation of cell shape and actin cytoskeletal organization(PubMed:15601624). Plays a role in actin organization by generating a loss of actin stress fibers and the formation of membrane ruffles and filopodia(PubMed:14662653). Required for SRC-induced podosome formation(By similarity). Involved in positive regulation of immature dendritic cell migration(By similarity).
Immunogen
Rho guanine nucleotide exchange factor(GEF) 5
Observed MW
60 kDa
Uniprot ID
Q12774
Tested Application
ELISA, WB, IHC, IP
Recommended dilution
WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200
Gene ID
7984
Research Area
Signal Transduction

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100ug
Available: In stock
available

Delivery expected until 6/27/2024 

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