Comparison

anti- ATG12 antibody

Manufacturer FineTest
Category
Type Antibody Monoclonal
Specific against Human, Mouse
Isotype IgG
Format liquid
Amount 100ug
Host Rabbit
Item no. FNab00666-100ug
eClass 6.1 32160702
eClass 9.0 42030590
Available
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Clonality
polyclonal
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20C for 12 months(Avoid repeated freeze / thaw cycles.)
Background
Ubiquitin-like protein involved in autophagy vesicles formation. Conjugation with ATG5 through a ubiquitin-like conjugating system involving also ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essential for its function. The ATG12-ATG5 conjugate acts as an E3-like enzyme which is required for lipidation of ATG8 family proteins and their association to the vesicle membranes. The ATG12-ATG5 conjugate also regulates negatively the innate antiviral immune response by blocking the type I IFN production pathway through direct association with RARRES3 and MAVS. Plays also a role in translation or delivery of incoming viral RNA to the translation apparatus.
Immunogen
ATG12 autophagy related 12 homolog(S. cerevisiae)
Observed MW
48-50kd
Uniprot ID
O94817
Tested Application
ELISA, WB, IHC, IP
Recommended dilution
WB: 1:500-1:2000; IP: 1:500-1:2000 ; IHC: 1:20-1:200
Gene ID
9140
Research Area
Epigenetics, Immunology, Cardiovascular, Metabolism

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100ug
Available: In stock
available

Delivery expected until 6/27/2024 

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