Comparison

ATG12 antibody

Item no. FNab00666-100ug
Manufacturer FineTest
Amount 100 ug
Quantity options 100 ug 100 ug 100 ug
Category
Type Antibody Monoclonal
Format Liquid
Applications WB, IP, IHC, ELISA
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host Rabbit
Isotype IgG
Purity ≥95% as determined by SDS-PAGE
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias Ubiquitin-like protein ATG12,Autophagy-related protein 12 (APG12-like),ATG12,APG12,APG12L
Available
Manufacturer - Targets
ATG12
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
Background
Ubiquitin-like protein involved in autophagy vesicles formation. Conjugation with ATG5 through a ubiquitin-like conjugating system involving also ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essential for its function. The ATG12-ATG5 conjugate acts as an E3-like enzyme which is required for lipidation of ATG8 family proteins and their association to the vesicle membranes. The ATG12-ATG5 conjugate also regulates negatively the innate antiviral immune response by blocking the type I IFN production pathway through direct association with RARRES3 and MAVS. Plays also a role in translation or delivery of incoming viral RNA to the translation apparatus.
Clonality
polyclonal
Immunogen
ATG12 autophagy related 12 homolog
Observed MW
48-50 kDa
Purification
Immunogen affinity purified
Recommended dilution
WB: 1:500-1:2000; IP: 1:500-1:2000 ; IHC: 1:20-1:200
Manufacturer - Research Area
Epigenetics, Immunology, Cardiovascular, Metabolism

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ug
Available: In stock
available

Delivery expected until 7/24/2025 

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