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AURKB antibody

AURKB antibody

Item no.	FNab00747-100ug
Manufacturer	FineTest
Amount	100 ug
Quantity options	100 ug 100 ug
Category	Antibodies Primary Antibodies
Type	Antibody Monoclonal
Format	Liquid
Applications	WB, IHC, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Purity	≥95% as determined by SDS-PAGE
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Aurora kinase B,Aurora 1,Aurora- and IPL1-like midbody-associated protein 1 (AIM-1),Aurora/IPL1-related kinase 2 (ARK-2,Aurora-related kinase 2),STK-1,Serine/threonine-protein kinase 12,Serine/threonine-protein kinase 5,Serine/threonine-protein kinase aurora-B,AURKB,AIK2,AIM1,AIRK2,ARK2,STK1,STK12,STK5
Available
Manufacturer - Targets	AURKB
Storage Conditions	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
Background	Aurora B(AURKB) is also named as aurora kinase B, AIK2, AIM1, AIRK2, ARK2, STK1, STK12, STK5 and belongs to the Aurora subfamily. Aurora kinase B is a chromosomal passenger serine/threonine protein kinase that regulates accurate chromosomal segregation, cytokinesis, protein localization to the centromere and kinetochore, correct microtubule-kinetochore attachments, and regulation of the mitotic checkpoint(PMID:18311747). Expression levels of AURKB are increased in the anaplastic thyroid carcinoma cell lines ARO, Cal 62, and KAT-4(PMID:15562011).
Clonality	polyclonal
Immunogen	aurora kinase B
Observed MW	16 kDa, 35-45 kDa
Purification	Immunogen affinity purified
Recommended dilution	WB: 1:200-1:2000; IHC: 1:20-1:200
Manufacturer - Research Area	Cancer, Cell Division and Proliferation, Metabolism
Manufacturer - Synonym	Aurora kinase B, Aurora 1, Aurora- and IPL1-like midbody-associated protein 1 (AIM-1), Aurora/IPL1-related kinase 2 (ARK-2, Aurora-related kinase 2), STK-1, Serine/threonine-protein kinase 12, Serine/threonine-protein kinase 5, Serine/threonine-protein kinase aurora-B, AURKB, AIK2, AIM1, AIRK2, ARK2, STK1, STK12, STK5

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