Comparison

BBS2 antibody

Item no. FNab00815-100ug
Manufacturer FineTest
Amount 100 ug
Quantity options 100 ug 100 ug
Category
Type Antibody Monoclonal
Format Liquid
Applications WB, IF, IP, ELISA
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Rabbit
Isotype IgG
Purity ≥95% as determined by SDS-PAGE
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias Bardet-Biedl syndrome 2 protein,BBS2
Available
Manufacturer - Targets
BBS2
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
Background
The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the guanosyl exchange factor(GEF) for Rab8 and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier vesicles to the base of the ciliary membrane. The BBSome complex, together with the LTZL1, controls SMO ciliary trafficking and contributes to the sonic hedgehog(SHH) pathway regulation. Required for proper BBSome complex assembly and its ciliary localization.
Clonality
polyclonal
Immunogen
Bardet-Biedl syndrome 2
Observed MW
80 kDa
Purification
Immunogen affinity purified
Recommended dilution
WB: 1:500-1:1000; IP: 1:200-1:1000; IF: 1:20-1:200
Manufacturer - Research Area
Neuroscience, Metabolism

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ug
Available: In stock
available

Delivery expected until 7/24/2025 

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