Comparison

anti- BCL2 antibody

Item no. FNab00840-100ug
Manufacturer FineTest
Amount 100ug
Category
Type Antibody Monoclonal
Format liquid
Clone 8A10
Specific against Human (Homo sapiens)
Host Mouse
Isotype IgG2a
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias Apoptosis regulator Bcl 2, B cell CLL/lymphoma 2, BCL2, Oncogene B cell leukemia 2
Available
Purification
Protein A+G purification
Purity
>=95% as determined by SDS-PAGE
Clonality
monoclonal
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20C for 12 months(Avoid repeated freeze / thaw cycles.)
Background
Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor(APAF-1). May attenuate inflammation by impairing NLRP1-inflammasome activation, hence CASP1 activation and IL1B release(PubMed:17418785).
Immunogen
B-cell CLL/lymphoma 2
Observed MW
26 kDa
Uniprot ID
P10415
Tested Application
ELISA, WB, IP, IHC
Recommended dilution
WB: 1:1000-1:10000; IP: 1:500-1:5000; IHC: 1:100-1:2000
Gene ID
596
Research Area
Neuroscience, Cancer, Immunology, Cardiovascular

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100ug
Available: In stock
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