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BCL2 antibody

BCL2 antibody

Item no.	FNab00840-100ug
Manufacturer	FineTest
Amount	100 ug
Quantity options	100 ug 100 ug
Category	Antibodies Primary Antibodies
Type	Antibody Monoclonal
Format	Liquid
Applications	WB, IP, IHC, ELISA
Clone	8A10
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG2a
Purity	≥95% as determined by SDS-PAGE
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Apoptosis regulator Bcl-2,BCL2
Available
Manufacturer - Targets	BCL2
Storage Conditions	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
Background	Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor(APAF-1). May attenuate inflammation by impairing NLRP1-inflammasome activation, hence CASP1 activation and IL1B release(PubMed:17418785).
Clonality	monoclonal
Immunogen	B-cell CLL/lymphoma 2
Observed MW	26 kDa
Purification	Protein A+G purification
Recommended dilution	WB: 1:1000-1:10000; IP: 1:500-1:5000; IHC: 1:100-1:2000
Manufacturer - Research Area	Neuroscience, Cancer, Immunology, Cardiovascular

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.