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BEX2 antibody

BEX2 antibody

Item no.	FNab00884-100ug
Manufacturer	FineTest
Amount	100 ug
Category	Antibodies Primary Antibodies
Type	Antibody Monoclonal
Format	Liquid
Applications	WB, IHC, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Purity	≥95% as determined by SDS-PAGE
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Protein BEX2,Brain-expressed X-linked protein 2 (hBex2),BEX2
Available
Manufacturer - Targets	BEX2
Storage Conditions	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
Background	Regulator of mitochondrial apoptosis and G1 cell cycle in breast cancer. Protects the breast cancer cells against mitochondrial apoptosis and this effect is mediated through the modulation of BCL2 protein family, which involves the positive regulation of anti-apoptotic member BCL2 and the negative regulation of pro-apoptotic members BAD, BAK1 and PUMA. Required for the normal cell cycle progression during G1 in breast cancer cells through the regulation of CCND1 and CDKN1A. Regulates the level of PP2A regulatory subunit B and PP2A phosphatase activity. The homology between human BEX1 and BEX2 is 94%. This antibody detects both BEX1 and BEX2.
Clonality	polyclonal
Immunogen	brain expressed X-linked 2
Observed MW	10-15 kDa
Purification	Immunogen affinity purified
Recommended dilution	WB: 1:500-1:1000; IHC: 1:20-1:200
Manufacturer - Research Area	Neuroscience, Signal Transduction, Cancer

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.