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anti- ITM2C antibody

anti- ITM2C antibody

Item no.	FNab04419-100ug
Manufacturer	FineTest
Amount	100 ug
Quantity options	100 ug 100 ug
Category	Antibodies Primary Antibodies
Type	Antibody Monoclonal
Format	Liquid
Applications	WB, IF, ELISA
Clone	5D9
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG2a
Purity	>=95% as determined by SDS-PAGE
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	BRI3
Available
Storage Conditions	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20C for 12 months(Avoid repeated freeze / thaw cycles.)
Background	Negative regulator of beta amyloid peptide production. May inhibit the processing of APP by blocking its access to alpha-and beta-secretase. Binding to the beta-secretase-cleaved APP C-terminal fragment is negligible, suggesting that ITM2C is a poor gamma-secretase cleavage inhibitor. May play a role in TNF-induced cell death and neuronal differentiation(By similarity).
Clonality	monoclonal
Immunogen	integral membrane protein 2C
Observed MW	35 kDa
Purification	Protein A+G purification
Recommended dilution	WB: 1:500-1:1000; IF: 1:20-1:200
Manufacturer - Research Area	Neuroscience

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.