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STIM1 antibody

STIM1 antibody

Item no.	FNab08321-100ug
Manufacturer	FineTest
Amount	100 ug
Quantity options	100 ug 100 ug
Category	Antibodies Primary Antibodies
Type	Antibody Monoclonal
Format	Liquid
Applications	WB, IHC, ELISA
Clone	4G6
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Mouse
Isotype	IgG2a
Purity	≥95% as determined by SDS-PAGE
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Stromal interaction molecule 1,STIM1,GOK
Available
Manufacturer - Targets	STIM1
Storage Conditions	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
Background	Plays a role in mediating store-operated Ca(2+) entry(SOCE), a Ca(2+) influx following depletion of intracellular Ca(2+) stores(By similarity). Acts as Ca(2+) sensor in the endoplasmic reticulum via its EF-hand domain. Upon Ca(2+) depletion, translocates from the endoplasmic reticulum to the plasma membrane where it activates the Ca(2+) release-activated Ca(2+)(CRAC) channel subunit ORAI1(PubMed:16208375). Involved in enamel formation(By similarity). Activated following interaction with TMEM110/STIMATE, leading to promote STIM1 conformational switch(By similarity).
Clonality	monoclonal
Immunogen	stromal interaction molecule 1
Observed MW	77 kDa
Purification	Protein A+G purification
Recommended dilution	WB: 1:200-1:2000IHC: 1:50-1:500
Manufacturer - Research Area	Neuroscience, Immunology

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.