Comparison

Golimumab European Partner

Item no. HY-P99111-5mg
Manufacturer MedChem Express
CASRN 476181-74-5
Amount 5 mg
Quantity options 100 mg 1 ea 1 mg 5 mg
Category
Type Biosimilars
Specific against other
Purity 99.71
Citations [1]Ueda N, et, al. The cytotoxic effects of certolizumab pegol and golimumab mediated by transmembrane tumor necrosis factor α. Inflamm Bowel Dis. 2013 May;19(6):1224-31.
[2]Pavitrakar V, et, al. Amelioration of Cisplatin-induced Renal Inflammation by Recombinant Human Golimumab in Mice. Curr Pharm Biotechnol. 2022;23(7):970-977.
[3]Shealy DJ, et, al. Characterization of golimumab, a human monoclonal antibody specific for human tumor necrosis factor α. MAbs. 2010 Jul-Aug;2(4):428-39.
Smiles [Golimumab]
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias CNTO-148
Shipping condition Cool pack
Available
Manufacturer - Type
Inhibitory Antibodies
Manufacturer - Applications
COVID-19-immunoregulation
Manufacturer - Targets
Apoptosis; Caspase; Interleukin Related; TNF Receptor
Shipping Temperature
Blue Ice
Storage Conditions
Store at 4°C for 2 years, do not freeze
Product Description
Golimumab (CNTO-148) is a potent human IgG1 TNFα antagonist monoclonal antibody. Golimumab has anti-inflammation activitity and inhibits IL-6 and IL-1β production. Golimumab acts via targeting and neutralizing TNF to prevent inflammation and destruction of cartilage and bone. Golimumab has the anticancer activity and induces cell apoptosis. Golimumab can be used for rheumatoid arthritis, Crohn's disease and cancer research[1][2][3].
Manufacturer - Research Area
Cancer; Inflammation/Immunology
Solubility
H2O
Manufacturer - Pathway
Apoptosis; Immunology/Inflammation
Isoform
IL-1; IL-6; TNFRSF5/CD40
Clinical information
Launched

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 5 mg
Available: In stock
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