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Golimumab

Golimumab

Item no.	HY-P99111-5mg
Manufacturer	MedChem Express
CASRN	476181-74-5
Amount	5 mg
Quantity options	100 mg 1 ea 1 mg 5 mg
Category	Antibodies In Vivo Antibodies
Type	Biosimilars
Specific against	other
Purity	99.71
Citations	[1]Ueda N, et, al. The cytotoxic effects of certolizumab pegol and golimumab mediated by transmembrane tumor necrosis factor α. Inflamm Bowel Dis. 2013 May;19(6):1224-31. [2]Pavitrakar V, et, al. Amelioration of Cisplatin-induced Renal Inflammation by Recombinant Human Golimumab in Mice. Curr Pharm Biotechnol. 2022;23(7):970-977. [3]Shealy DJ, et, al. Characterization of golimumab, a human monoclonal antibody specific for human tumor necrosis factor α. MAbs. 2010 Jul-Aug;2(4):428-39.
Smiles	[Golimumab]
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	CNTO-148
Shipping condition	Cool pack
Available
Manufacturer - Type	Inhibitory Antibodies
Manufacturer - Applications	COVID-19-immunoregulation
Manufacturer - Targets	Apoptosis; Caspase; Interleukin Related; TNF Receptor
Shipping Temperature	Blue Ice
Storage Conditions	Store at 4°C for 2 years, do not freeze
Product Description	Golimumab (CNTO-148) is a potent human IgG1 TNFα antagonist monoclonal antibody. Golimumab has anti-inflammation activitity and inhibits IL-6 and IL-1β production. Golimumab acts via targeting and neutralizing TNF to prevent inflammation and destruction of cartilage and bone. Golimumab has the anticancer activity and induces cell apoptosis. Golimumab can be used for rheumatoid arthritis, Crohn's disease and cancer research[1][2][3].
Manufacturer - Research Area	Cancer; Inflammation/Immunology
Solubility	H2O
Manufacturer - Pathway	Apoptosis; Immunology/Inflammation
Isoform	IL-1; IL-6; TNFRSF5/CD40
Clinical information	Launched

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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HY-P99111-5mg-safety-datasheet.pdf