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Alemtuzumab

Alemtuzumab

Item no.	HY-P9948-2mg
Manufacturer	MedChem Express
CASRN	216503-57-0
Amount	2 mg
Quantity options	10 mg 1 mg 25 mg 2 mg 50 mg 5 mg
Category	Antibodies Primary Antibodies
Type	Antibody
Specific against	other
Purity	97.15
Dry ice	Yes
Citations	[1]Kashani N, et al. Immune Regulatory Cell Bias Following Alemtuzumab Treatment in Relapsing-Remitting Multiple Sclerosis. Front Immunol. 2021;12:706278. Published 2021 Oct 28. \|[2]Yanping Hu, et al. Investigation of the mechanism of action of alemtuzumab in a human CD52 transgenic mouse model. Immunology. 2009 Oct;128(2):260-70.
Smiles	[Alemtuzumab]
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Campath-IH
Shipping Condition	Dry ice
Available
Manufacturer - Type	Inhibitory Antibodies
Manufacturer - Applications	Cancer-programmed cell death
Manufacturer - Targets	Apoptosis
Shipping Temperature	Dry Ice
Storage Conditions	Store at -80°C for 2 years
Molecular Weight	(146.06 kDa)
Product Description	Alemtuzumab (Campath-IH) is a humanized monoclonal antibody against CD52. Alemtuzumab does not cross-react with murine CD52. Alemtuzumab selectively targets the CD52 antigen to induce profound lymphocyte depletion, followed by recovery of T and B cells with regulatory phenotypes. Alemtuzumab is capable of complement-dependent cytotoxicity and antibody-dependent cell-mediated cytotoxicity (ADCC), as well as induction of apoptosis. Alemtuzumab has the potential for B-cell chronic lymphocytic leukaemia research[1][2].
Manufacturer - Research Area	Cancer
Solubility	H2O
Manufacturer - Pathway	Apoptosis
Clinical information	Launched

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HY-P9948-2mg-safety-datasheet.pdf