Comparison
Antibodies

Anti-Human CD16 In Vivo Antibody - Low Endotoxin (3G8) European Partner

Manufacturer IchorBio
Category
Type Antibody
Specific against Human
Clone 3G8
Isotype IgG1 Kappa
Applications FC, IHC, Blocking
Amount 1mg
Host Mouse
Item no. ICH1010-1MG
Targets CD16
eClass 6.1 32160702
eClass 9.0 32160702
Available
Aggregation
Aggregation level <= 5%
Antigen Distribution
CD16 is expressed on the surface of NK cells, activated monocytes, macrophages, and placental trophoblasts in humans.
Application Notes
Flow Cytometry: For flow cytometric staining, the suggested use of this reagent is <=2.0 ug per million cells in 100 ul volume. Blocking: Clone 3G8 antibody blocks neutrophil phagocytosis and stimulates NK cell proliferation. Each investigator should determine their own optimal working dilution for specific applications.
Background
CD16 is known as low affinity IgG receptor III (Fc gamma RIII) and is expressed as two distinct forms (CD16a and CD16b). CD16a (Fc gamma RIIIA) is a 50-65 kD polypeptide-anchored transmembrane protein. CD16b (Fc gamma RIIIB) is a 48 kD glycosylphosphatidylinositol (GPI)-anchored protein. Its extracellular domain is over 95% homologous to that of CD16a, and it is expressed specifically on neutrophils.
Concentration
>= 2.0 mg/ml
Endotoxin
<= 1.0 EU/mg as determined by the LAL method
Formulation
0.01 M phosphate buffered saline (PBS) pH 7.4, 150 mM NaCl, without BSA or sodium azide added.
Immunogen
Human PMN cells
Product Type
Low Endotoxin, anti-human
Purification method
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Storage
anti-CD16 In Vivo Antibody - Low Endotoxin (3G8) is stable when stored at 2-8C.
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 1mg
Available: In stock
available

Delivery expected until 6/20/2024 

Compare

Add to wishlist

Get an offer

Request delivery time

Ask a technical question

Submit a bulk request

Questions about this Product?
 
Close