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Anti-Mouse TCR gamma/delta In Vivo Antibody - Low Endotoxin (UC7-13D5)

Anti-Mouse TCR gamma/delta In Vivo Antibody - Low Endotoxin (UC7-13D5)

Manufacturer	IchorBio
Category	In Vivo Antibodies In Vivo Antibodies Flow Cytometry
Type	Antibody
Specific against	Mouse
Clone	UC7-13D5
Isotype	IgG
Applications	FC, IP, IV
Amount	50mg
Host	Hamster - Armenian
Item no.	ICH1035-50MG
eClass 6.1	32160702
eClass 9.0	32160702
Available
Manufacturers Product Category	Low Endotoxin, anti-mouse
Target Information	TCR gamma/delta
Isotype Information	Armenian Hamster IgG
Antigen Distribution	gamma/delta TCR expression is observed on a subset of cells in the thymus, intestinal epithelium, skin, liver, peripheral lymphoid tissues, and peritoneum. The gamma/delta TCR is involved in the antigen recognition of some bacterial or tumor-associated antigens presented by MHC class I.
Background	The T cell receptor or TCR is a molecule found on the surface of T lymphocytes that is responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules. It is a heterodimer consisting of an alpha and beta chain in 95% of T cells, while 5% of T cells have TCRs consisting of gamma and delta chains. Engagement of the TCR with antigen and MHC results in activation of its T lymphocyte through a series of biochemical events mediated by associated enzymes, co-receptors and specialized accessory molecules.
Immunogen	Unknown
Concentration	≥ 2.0 mg/ml
Formulation	0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added.
Endotoxin	≤ 1.0 EU/mg as determined by the LAL method
Aggregation	Aggregation level ≤ 5%
Storage	anti-TCR gamma/delta In Vivo Antibody - Low Endotoxin (UC7-13D5) is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Application Notes	In vivo Depletion: This Clone UC7-13D5 has been used for the depletion of TCR gamma/delta T cells in vivo - Each investigator should determine their own optimal working dilution for specific applications.
Use	Products are for research use only. Not for use in diagnostic or therapeutic procedures.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50mg

available

Delivery expected until 6/6/2024