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Anti-Mouse CD54 (YN1/1.7.4) In Vivo Antibody - Low Endotoxin

Anti-Mouse CD54 (YN1/1.7.4) In Vivo Antibody - Low Endotoxin

Item no.	ICH1059-100MG
Manufacturer	IchorBio
Amount	100 mg
Quantity options	100 mg 1 mg 25 mg 50 mg 5 mg
Category	Oncology Neuroscience Neural Lineage Markers Antibodies In Vivo Antibodies By Cell Type Hematology Myeloma Cell Biology Cell Movement Cell Adhesion Western Blot
Type	Antibody
Applications	WB, FC, IP, IHC, FA
Clone	YN1/1.7.4
Specific against	Mouse (Murine, Mus musculus)
Host	Rat
Isotype	IgG2b Kappa
Purity	>95% by SDS-PAGE and HPLC
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Intercellular adhesion molecule 1, Icam1, MALA-2, MyD10
Shipping Condition	Cool pack
Available
Specificity	Anti-CD54 In Vivo Antibody - Low Endotoxin (YN1/1.7.4) recognizes an epitope on Mouse ICAM-1
Manufacturer - Applications	Western Blot, Functional Assays, Flow Cytometry, IHC (Frozen), Immunoprecipitation
Manufacturer - Category	Low Endotoxin, anti-mouse, monoclonal antibody
Manufacturer - Isotype	Rat IgG2b Kappa
Manufacturer - Targets	CD54
Shipping Temperature	Blue ice
Storage Conditions	anti-CD54 In Vivo Antibody - Low Endotoxin (YN1/1.7.4) is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
Aggregation	Aggregation level ≤ 5%
Formulation	0.01 M phosphate buffered saline (PBS) pH 7.2 - 7.4, 150 mM NaCl with no carrier protein, potassium or preservatives added.
Antigen Distribution	The CD54 antigen is present on endothelial cells, lymphocytes, epithelial cells, dendritic cells and keratinocytes. It has been demonstrated that ICAM-1 enhances T-cell activation.
Application Notes	Each investigator should determine their own optimal working dilution for specific applications.
Background	Intercellular adhesion molecule-1 (ICAM-1) is one of an important cell adhesion molecules (CAMs) family transmembrane glycoprotein and is critical for the firm arrest and transmigration of leukocytes out of blood vessels and into tissues. ICAM-1 is constitutively present on endothelial cells, but its expression is increased by proinflammatory cytokines. ICAM-1 is a marker of endothelial dysfunction leading to damaging vascular disorders, in umbilical and placental vascular tissue of gestational pregnancies.
Concentration	1.0 mg/ml
Endotoxin	≤ 1.0 EU/mg as determined by the LAL method
Manufacturer - Specificity	Anti-CD54 In Vivo Antibody - Low Endotoxin (YN1/1.7.4) recognizes an epitope on Mouse ICAM-1
Purification method	This monoclonal antibody was purified using Protein G
Use	Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Immunogen	Mouse NS-1 cells
Isotype Control	Rat IgG2b In Vivo Isotype Control - Low Endotoxin [1-2] (ICH2243)
Buffer	ICH3001-100ml; ICH3002-100ml; ICH3003-100ml

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 mg

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Delivery expected until 9/4/2025

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