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Anti-Mouse CD70 In Vivo Antibody - Low Endotoxin (FR70)

Anti-Mouse CD70 In Vivo Antibody - Low Endotoxin (FR70)

Manufacturer	IchorBio
Category	Antibodies In Vivo Antibodies Western Blot Blocking
Type	Antibody
Specific against	Mouse
Clone	FR70
Isotype	IgG2b Kappa
Applications	WB, Blocking
Amount	0.5mg
Host	Rat
Item no.	ICH1061-0.5MG
eClass 6.1	32160702
eClass 9.0	32160702
Available
Target	CD70
Aggregation	Aggregation level <= 5%
Antigen Distribution	The CD70 antigen is expressed by activated B cells and some activated T cells.
Application Notes	Each investigator should determine their own optimal working dilution for specific applications.
Background	CD70 is a 30-33 kDa type II transmembrane protein. It is a member of the TNF superfamily, expressed on activated B cells, activated dendritic cells, and some activated T cells (low levels). CD70 interacts with CD27 to promote T-B cell cross-stimulation and co-stimulate B cell proliferation and immunoglobulin production. Cells expressing CD70 can co-stimulate T cell proliferation and enhance the production of cytokines. The FR70 antibody blocks CD70 binding to CD27.
Concentration	1.0 mg/ml
Endotoxin	<= 1.0 EU/mg as determined by the LAL method
Formulation	0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added.
Immunogen	BALB/c mouse B lymphoma A20.J2
Product Type	Low Endotoxin, anti-mouse
Purification method	This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Storage	anti-CD70 In Vivo Antibody - Low Endotoxin (FR70) is stable for at least one week when stored sterile at 2-8C. For long term storage aseptically aliquot in working volumes without diluting and store at -80C. Avoid Repeated Freeze Thaw Cycles.
Use	Products are for research use only. Not for use in diagnostic or therapeutic procedures.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.5mg

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Delivery expected until 6/6/2024