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Anti-Mouse ICAM-1 (BE29G1) In Vivo Antibody - Low Endotoxin

Anti-Mouse ICAM-1 (BE29G1) In Vivo Antibody - Low Endotoxin

Item no.	ICH1101-25MG
Manufacturer	IchorBio
Amount	25 mg
Quantity options	100 mg 1 mg 25 mg 50 mg 5 mg
Category	Oncology Neuroscience Neural Lineage Markers Antibodies In Vivo Antibodies By Cell Type Hematology Myeloma Cell Biology Cell Movement Cell Adhesion Western Blot Blocking
Type	Antibody
Applications	WB, IP, Blocking
Clone	BE29G1
Specific against	Mouse (Murine, Mus musculus)
Host	Rat
Isotype	IgG2a
Purity	>95% by SDS-PAGE and HPLC
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Intercellular adhesion molecule 1, Icam1, MALA-2, MyD10, CD54
Shipping Condition	Cool pack
Available
Specificity	Anti-ICAM-1 In Vivo Antibody - Low Endotoxin (BE29G1) recognizes the (Mr 95 kD) cell surface glycoprotein known as intracellular adhesion molecule ICAM-1. ICAM-1 is the receptor for LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18).
Manufacturer - Applications	Immunoprecipitation, Western Blot, Blocking
Manufacturer - Category	Low Endotoxin, anti-mouse, monoclonal antibody
Manufacturer - Isotype	Rat IgG2a
Manufacturer - Targets	ICAM-1
Shipping Temperature	Blue ice
Storage Conditions	anti-ICAM-1 In Vivo Antibody - Low Endotoxin (BE29G1) is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
Aggregation	Aggregation level ≤ 5%
Formulation	0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added.
Antigen Distribution	The CD54 antigen is present on endothelial cells, lymphocytes, epithelial cells, dendritic cells and keratinocytes. It has been demonstrated that ICAM-1 enhances T-cell activation.
Application Notes	Blocking: This antibody blocks the binding LFA-1 (CD11a/CD18) to ICAM-1. The antibody is suitable for studies of inflammation, lymphocyte differentiation, and lymphocyte activation. Each investigator should determine their own optimal working dilution for specific applications.
Background	Intercellular adhesion molecule-1 (ICAM-1) is one of an important cell adhesion molecules (CAMs) family transmembrane glycoprotein and is critical for the firm arrest and transmigration of leukocytes out of blood vessels and into tissues. ICAM-1 is constitutively present on endothelial cells, but its expression is increased by proinflammatory cytokines. ICAM-1 is a marker of endothelial dysfunction leading to damaging vascular disorders, in umbilical and placental vascular tissue of gestational pregnancies
Concentration	0.5 mg/ml
Endotoxin	≤ 1.0 EU/mg as determined by the LAL method
Manufacturer - Specificity	Anti-ICAM-1 In Vivo Antibody - Low Endotoxin (BE29G1) recognizes the (Mr 95 kD) cell surface glycoprotein known as intracellular adhesion molecule ICAM-1. ICAM-1 is the receptor for LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18).
Purification method	This monoclonal antibody was purified using Protein G
Use	Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Immunogen	Purified Recombinant Mouse ICAM-1 (>98%)
Antibodies against the same target (Cat No.)	ICH1027-1MG
Isotype Control	Rat IgG2a In Vivo Isotype Control - Low Endotoxin [1-1] (ICH2244)
Buffer	ICH3001-100ml; ICH3002-100ml; ICH3003-100ml

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 25 mg

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Delivery expected until 12/4/2025

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