Anti-Mouse IL-2 In Vivo Antibody - Low Endotoxin (JES6-1A12)

Low Endotoxin, anti-mouse

anti-IL-2 In Vivo Antibody - Low Endotoxin (JES6-1A12) is stable when stored at 2-8C. Do not freeze.

0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added.

Interleukin-2 (IL-2) is a potent T-cell mitogenic cytokine that functions as a primary regulator of T cell homeostasis and has been considered a prime candidate immunotherapeutics, both for increasing T cell levels/function and for augmenting vaccine-elicited viral-specific T cell responses. IL-2 plays a key role in setting the balance between immunity and tolerance. This cytokine has a dual role as the regulator of the two main phases of the immune response (proliferative and suppressive). IL-2 also stimulates growth and differentiation of B cells, NK cells, LAK cells, monocytes, and oligodendrocytes. The JES6-1A12 antibody has been shown to neutralize IL-2 in vivo.

<= 1.0 EU/mg as determined by the LAL method

Products are for research use only. Not for use in diagnostic or therapeutic procedures.