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Anti-CD45R (RA3-6B2) In Vivo Antibody - Low Endotoxin

Anti-CD45R (RA3-6B2) In Vivo Antibody - Low Endotoxin

Item no.	ICH1130-50MG
Manufacturer	IchorBio
Amount	50 mg
Quantity options	100 mg 1 mg 25 mg 50 mg 5 mg
Category	Oncology Neuroscience Neural Lineage Markers Antibodies In Vivo Antibodies By Cell Type Carcinoma Hematology Leukemia Western Blot Progenitor Markers
Type	Antibody
Applications	WB, FC, IF, IP, IHC, ELISA, FA
Clone	RA3-6B2
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rat
Isotype	IgG2a
Purity	>95% by SDS-PAGE and HPLC
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Leukocyte common antigen, L-CA, T200, CD45, Receptor-type tyrosine-protein phosphatase C, PTPRC, B220
Shipping Condition	Cool pack
Available
Specificity	Anti-CD45R In Vivo Antibody - Low Endotoxin (RA3-6B2) recognizes the B-cell determinant (Mr 220 kD) of the CD45 molecule.
Manufacturer - Applications	Western Blot, Functional Assays, Flow Cytometry, IHC (Frozen), IHC (Paraffin), Immunoprecipitation, Immunofluorescence, ELISA
Manufacturer - Category	Low Endotoxin, anti-mouse, anti-human, monoclonal antibody
Manufacturer - Isotype	Rat IgG2a
Manufacturer - Targets	CD45R
Shipping Temperature	Blue ice
Storage Conditions	Anti-CD45R In Vivo Antibody - Low Endotoxin (RA3-6B2) is stable for at least four (4) weeks when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at –80°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Aggregation	Aggregation level ≤ 5%
Formulation	No carrier proteins or preservatives added in 0.01 M phosphate buffered saline (PBS) pH 7.4, 150 mM NaCl.
Antigen Distribution	The CD45R antigen is present on mouse B-cells, B-cell precursors, T cell subset, NK cell subsets .
Application Notes	Functional Assay: In vivo treatment with Rat Anti-Mouse CD45R (Clone RA3-6B2) reduces the number of T and B cells and modifies their functional activity. Each investigator should determine their own optimal working dilution for specific applications.
Background	CD45R, also known as B220 is a 220 kDa transmembrane protein tyrosine phosphatase expressed on B cells and some subsets of T and NK cells. This antibody is commonly used as a B cell marker as CD45R does play a critical role in TCR and BCR signaling.
Concentration	0.5 mg/ml
Endotoxin	≤ 1.0 EU/mg as determined by the LAL method
Manufacturer - Specificity	Anti-CD45R In Vivo Antibody - Low Endotoxin (RA3-6B2) recognizes the B-cell determinant (Mr 220 kD) of the CD45 molecule.
Purification method	This monoclonal antibody was purified using Protein G
Use	Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Immunogen	Abelson murine leukemia virus-induced pre-B tumor cells
Related Antibodies	Anti-CD45R In Vivo Antibody - Ultra Low Endotoxin [RA3-6B2] (ICH1130UL)
Antibodies against the same target (Cat No.)	ICH1057-1MG
Isotype Control	Rat IgG2a In Vivo Isotype Control - Low Endotoxin [1-1] (ICH2244)
Buffer	ICH3001-100ml; ICH3002-100ml; ICH3003-100ml

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 mg

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Delivery expected until 11/6/2025

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