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Anti-Mouse TNF Alpha (TN3-19.12) In Vivo Antibody - Low Endotoxin

Anti-Mouse TNF Alpha (TN3-19.12) In Vivo Antibody - Low Endotoxin

Item no.	ICH1136-5MG
Manufacturer	IchorBio
Amount	5 mg
Quantity options	100 mg 1 mg 25 mg 50 mg 5 mg
Category	Antibodies In Vivo Antibodies Western Blot
Type	Antibody
Applications	WB, FC, IP, Blocking, FA
Clone	TN3-19.12
Specific against	Mouse (Murine, Mus musculus)
Host	Hamster - Armenian
Isotype	IgG
Purity	>95% by SDS-PAGE and HPLC
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Cachectin, TNFa, Tumor necrosis factor ligand superfamily member 2, Tnfsf2
Shipping Condition	Cool pack
Available
Specificity	Anti-TNF alpha In Vivo Antibody - Low Endotoxin (TN3-19.12) recognizes Mouse TNFa
Manufacturer - Applications	Immunoprecipitation, Western Blot, Functional Assays, Flow Cytometry, Blocking
Manufacturer - Category	Low Endotoxin, anti-mouse, monoclonal antibody
Manufacturer - Isotype	Armenian Hamster IgG
Manufacturer - Targets	TNF alpha
Shipping Temperature	Blue ice
Storage Conditions	anti-TNF alpha In Vivo Antibody - Low Endotoxin (TN3-19.12) is stable for at least four (4) weeks when stored sterile at 2-8°C. For long-term storage aseptically aliquot in working volumes without diluting and store at –20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Aggregation	Aggregation level ≤ 5%
Formulation	0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added.
Antigen Distribution	Activated monocytes, neutrophils, macrophages, T cells, B cells, NK cells, LAK cells
Application Notes	Each investigator should determine their own optimal working dilution for specific applications.
Background	The tumor necrosis factor (TNF-alpha) is a multifaceted polypeptide cytokine known as a mediator of inflammation and immunity. It may mediate some of the significant changes in cellular homeostasis which accompany the invasion of the mammalian host by viruses, bacteria, and parasites. TNF-alpha is an acute phase protein which initiates a cascade of cytokines and increases vascular permeability, thereby recruiting macrophage and neutrophils to a site of infection. TNF-alpha secreted by the macrophage causes blood clotting which serves to contain the infection. TNF-alpha has been detected in synovial fluid of patients with rheumatoid arthritis. Clone TN3-19.12 antibody can neutralize the bioactivity of natural or recombinant TNF-alpha
Concentration	1.0 mg/ml
Endotoxin	≤ 1.0 EU/mg as determined by the LAL method
Manufacturer - Specificity	Anti-TNF alpha In Vivo Antibody - Low Endotoxin (TN3-19.12) recognizes Mouse TNFa
Purification method	This monoclonal antibody was purified using Protein A
Use	Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Immunogen	Recombinant mouse TNFalpha
Related Antibodies	Anti-TNF alpha In Vivo Antibody - Ultra Low Endotoxin [TN3-19.12 ] (ICH1136UL)
Antibodies against the same target (Cat No.)	Anti-TNF alpha In Vivo Antibody - Low Endotoxin [MP6-XT22] (ICH1127)
Isotype Control	Armenian Hamster IgG Isotype Control for In Vivo - Low Endotoxin [PIP] (ICH2251)
Buffer	ICH3001-100ml; ICH3002-100ml; ICH3003-100ml

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 5 mg

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Delivery expected until 9/4/2025

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