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Anti-Mouse DNGR-1 In Vivo Antibody – Low Endotoxin (1F6) [ICH1168]

Anti-Mouse DNGR-1 In Vivo Antibody – Low Endotoxin (1F6) [ICH1168]

Manufacturer	IchorBio
Category	Antibodies In Vivo Antibodies Flow Cytometry Western Blot Immunofluorescence
Type	Antibody
Specific against	Mouse
Clone	1F6
Isotype	IgG1
Applications	WB, FC
Amount	50mg
Host	Rat
Item no.	ICH1168-50MG
eClass 6.1	32160702
eClass 9.0	32160702
Available
Manufacturers Product Category	Ultra-Low Endotoxin, anti-mouse
Target Information	CLEC9A
Isotype Information	Rat IgG1
Purification method	This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Antigen Distribution	CD370 (CLEC9A) in mice is expressed on CD8+ DCs and at low levels by plasmacytoid DCs.
Background	CLEC9A, also known as DNGR1 is defined as a type II membrane protein with a single extracellular C-type lectin domain¹. CLEC9A is involved with adaptive immune response during infection. Additionally, CLEC9A, is being investigated for potential to enhance immune responses produced by vaccines.
Immunogen	RBL-2H3 cells expressing mouse DNGR-1 fused to an HA epitope.
Concentration	>2.0 mg/ml
Formulation	This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (PBS) pH 7.2 – 7.4, 150 mM NaCl with no carrier protein, potassium or preservatives added. BSA and azide free
Endotoxin	≤ 1.0 EU/mg as determined by the LAL method
Aggregation	Aggregation level ≤ 5%
Storage	This antibody is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
Application Notes	Each investigator should determine their own optimal working dilution for specific applications.
Use	Products are for research use only. Not for use in diagnostic or therapeutic procedures.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50mg

available

Delivery expected until 6/6/2024