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Anti-Mouse Ly49C (4LO3311) In Vivo Antibody - Ultra-Low Endotoxin

Anti-Mouse Ly49C (4LO3311) In Vivo Antibody - Ultra-Low Endotoxin

Item no.	ICH1202UL-100mg
Manufacturer	IchorBio
Amount	100 mg
Quantity options	100 mg 25 mg 50 mg 5 mg
Category	Antibodies In Vivo Antibodies
Type	Antibody Monoclonal
Applications	FC, IP
Clone	4LO3311
Specific against	Mouse (Murine, Mus musculus)
Host	Mouse
Isotype	IgG3 Kappa
Purity	>98% by SDS-PAGE and HPLC
Formula	Sterile, preservative-free, solution in PBS. BSA and Azide free.
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Ly-49 inhibitory receptors C
Shipping Condition	Cool pack
Available
Specificity	4LO3311 activity is directed against Ly49C (Killer cell lectin-like receptor 3, KLRA3; NK2.1). 4LO3311 binds an epitope located in a 32-amino acid segment of the stalk region immediately adjacent to the carbohydrate recognition domain.
Manufacturer - Applications	Depletion, Flow Cytometry, Immunoprecipitation
Manufacturer - Category	Ultra-Low Endotoxin, anti-mouse, monoclonal antibody
Manufacturer - Isotype	Mouse IgG3 Kappa
Manufacturer - Targets	Ly49C
Shipping Temperature	Blue ice
Storage Conditions	This antibody is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
Aggregation	Aggregation level ≤ 1%
Formulation	Sterile, preservative-free, solution in PBS. BSA and Azide free.
Antigen Distribution	Ly49C is expressed on NK, uterine NK, NKT, and CD8+ T cells.
Application Notes	Each investigator should determine their own optimal working dilution for specific applications.
Background	4LO3311 recognizes an epitope located in a 32-amino acid segment of the stalk region immediately adjacent to the carbohydrate recognition domain. 4LO3311 recognizes Ly-49CBALB but not Ly-49AB6, Ly-49ABALB, BBALB, DB6, EB6, FB6, GB6, GBALB, or H. 4LO3311 plus complement inhibits NK cell and antibody-dependent cellular cytotoxicity (ADCC) activity in C3H spleen cells4. 4LO3311 inhibits C57BL/6 and C3H NK cell activity but has no effect on NZB NK cells.
Concentration	≥ 2.0 mg/ml
Endotoxin	≤ 0.5 EU/mg as determined by the LAL method
Manufacturer - Specificity	4LO3311 activity is directed against Ly49C (Killer cell lectin-like receptor 3, KLRA3; NK2.1). 4LO3311 binds an epitope located in a 32-amino acid segment of the stalk region immediately adjacent to the carbohydrate recognition domain.
Purification method	This monoclonal antibody was purified using Protein A
Use	Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Immunogen	4LO3311 was generated by immunizing 129/SvJ mice with C57BL/6 NK-enriched spleen cells
IMPACT Pathogen Test	We use the IMPACT test generated by IDEXX Laboratories to guarantee our Ultra Low Endotoxin antibodies are pathogen free. Our hamster antibodies are tested for: Mycoplasma spp Mycoplasma pulmonis Pneumonia virus of mice Kilham's rat virus Toolan's H1 virus Hamster parvovirus Lymphocytic choriomeningitis Minute virus of mice Theiler's murine encephalomyelitis virus Sendai virus Reovirus 3 Hantaan virus
Isotype Control	Mouse IgG3 Isotype Control for In Vivo - Low Endotoxin [MG3-35] (ICH2249)
Buffer	ICH3001-100ml; ICH3002-100ml; ICH3003-100ml

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 mg

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Delivery expected until 1/1/2026

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