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Tocilizumab Biosimilar - Research Grade

Tocilizumab Biosimilar - Research Grade

Manufacturer	IchorBio
Category	Antibodies In Vivo Antibodies
Type	Biosimilars
Specific against	Human
Isotype	IgG1 Kappa
Amount	5mg
Host	Humanized
Item no.	ICH4012-5MG
eClass 6.1	32160702
eClass 9.0	42030590
Available
Manufacturers Product Category	Low endotoxin, biosimilar antibody
Target Information	IL-6 receptor
Isotype Information	Human IgG1 Kappa
Host Information	Humanized
Purification method	This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Background	Tocilizumab is a recombinant humanized anti-human interleukin 6 (IL-6) receptor monoclonal antibody of the immunoglobulin IgG1κ (gamma 1, kappa) subclass with a typical H2L2 polypeptide structure. Each light chain and heavy chain consists of 214 and 448 amino acids, respectively. The four polypeptide chains are linked intra- and inter-molecularly by disulfide bonds. Tocilizumab has a molecular weight of approximately 148 kDa. The antibody is produced in mammalian (Chinese hamster ovary) cells.
Concentration	1.0 - 5.0 mg/ml
Formulation	Phosphate buffered saline (PBS) pH 7.2, with no carrier protein, potassium or preservatives added. BSA and Azide free.
Endotoxin	≤ 0.5 EU/mg as determined by the LAL method
Storage	Stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
Use	Products are for research use only. Not for use in diagnostic or therapeutic procedures.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 5mg

available

Delivery expected until 6/20/2024