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Anti-Human CX3CR1 (NT) - 0.1 mg

Anti-Human CX3CR1 (NT) - 0.1 mg

Item no.	LEIN-C1121-0.1mg
Manufacturer	Leinco Technologies
Amount	0.1 mg
Quantity options	0.1 mg 20 ug
Category	Oncology Neuroscience Neural Lineage Markers Neuroinflammation Antibodies By Cell Type Flow Cytometry Immunohistochemistry Western Blot Primary Antibodies
Type	Antibody Primary
Applications	WB, FC, IHC
Specific against	Human (Homo sapiens)
Host	Rabbit
Citations	1. Raport, C. J. et al. (1995) Gene 163:295 2. Combadiere, C. et al. (1995) DNA Cell Biol. 14:673 3. Combadiere. C. et al. (1998) Biochem. Biophys. Res. Commun. 253:728 4. Harrison, J. K. et al. (1994) Neurosci. Lett. 169:85
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Shipping Condition	Room temperature
Available
Manufacturer - Applications	FC, IHC FFPE, WB
Manufacturer - Category	Primary Monoclonal Antibodies>Infectious Diseases
Manufacturer - Targets	CX3CR1
Country of Origin	USA
Shipping Temperature	Next Day Ambient
Storage Conditions	This polyclonal antibody is stable for at least one week when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at –20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Product Description	CX3CR1 is one of the chemokine receptors that are required as coreceptors for HIV infection. The genes encoding human, mouse, and rat CX3CR1 were cloned and designated V28 and CMKBRL1, CX3CR1, and RBS11, respectively.1-4 The encoded seven transmembrane protein was recently identified as the receptor for a novel transmembrane molecule, fractalkine, and renamed CX3CR1. Recently, CX3CR1 was found to serve as a coreceptor for HIV-1 and HIV-2 envelope fusion and virus infection, which can be inhibited by fractokine. CX3CR1 mediates leukocyte migration and adhesion. CX3CR1 is expressed in a variety of human tissues and cell lines.2
Background	CX3CR1 is one of the chemokine receptors that are required as coreceptors for HIV infection. The genes encoding human, mouse, and rat CX3CR1 were cloned and designated V28 and CMKBRL1, CX3CR1, and RBS11, respectively.^1-4 The encoded seven transmembrane protein was recently identified as the receptor for a novel transmembrane molecule, fractalkine, and renamed CX3CR1. Recently, CX3CR1 was found to serve as a coreceptor for HIV-1 and HIV-2 envelope fusion and virus infection, which can be inhibited by fractokine. CX3CR1 mediates leukocyte migration and adhesion. CX3CR1 is expressed in a variety of human tissues and cell lines.²
PubMed	CX3CR1
Manufacturer - Specificity	Rabbit Anti-Human CX3CR1 recognizes an epitope near the N-terminus of Human, Mouse and Rat CX3CR1. This polyclonal antibody was purified using affinity chromatography.
RRID	AB_2828337
Concentration	0.5 mg/ml
Formulation	This polyclonal antibody is formulated in phosphate buffered saline (PBS) pH 7.4 containing 0.02% sodium azide as a preservative.
Additional Information	Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.
Keywords	CX3CR1 Antibody, V28, CCRL1, GPR13, CMKDR1, GPRV28, CMKBRL1, CX3C chemokine receptor 1, Beta chemokine receptor-like 1, C-X3-C CKR-1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

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LEIN-C1121-0.1mg-safety-datasheet.pdf