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Anti-Mouse CCL25 (Clone 89827) - 500 µg

Anti-Mouse CCL25 (Clone 89827) - 500 µg

Item no.	LEIN-C1429-500ug
Manufacturer	Leinco Technologies
Amount	500 ug
Quantity options	25 ug 500 ug
Category	Neuroscience Neuroinflammation Antibodies Immunohistochemistry Western Blot ELISA Primary Antibodies Immunostaining
Type	Antibody Monoclonal
Applications	WB, IHC, ELISA
Clone	89827
Specific against	Mouse (Murine, Mus musculus)
Host	Rat
Citations	1. Zlotnik, A. et al. (1997) Immunity. 7(2):291-301. 2. Agace, W. et al. (2006) J Immunol. 176:3642 3. Teixidó, J. et al. (2007) J Leukoc Biol. 82:380
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Shipping Condition	Room temperature
Available
Manufacturer - Applications	ELISA Cap, IHC FFPE, WB
Manufacturer - Category	Primary Monoclonal Antibodies>Growth Factors and Cytokines
Manufacturer - Targets	CCL25
Country of Origin	USA
Shipping Temperature	Next Day Ambient
Storage Conditions	The lyophilized antibody can be stored desiccated at -20°C to -70°C for up to twelve months. The reconstituted antibody can be stored for at least four weeks at 2-8°C. For long-term storage of the reconstituted antibody, aseptically aliquot into working volumes and store at -20°C to -70°C in a manual defrost freezer. Avoid repeated freeze thaw cycles. No detectable loss of activity was observed after six months.
Product Description	Chemokine (C-C motif) ligand 25 (CCL25) is a small cytokine belonging to the CC chemokine family that is also known as TECK (Thymus-Expressed ChemoKine). CCL25 is believed to play a role in the development of T-cells.1 It is chemotactic for thymocytes, macrophages, and dendritic cells. CCL25 is expressed in the small intestinal epithelium and plays an important role in mediating lymphocyte recruitment to this site.2 CCL25 is also highly expressed in the thymus, where it binds to its receptor CCR9 on thymocytes promoting migration and activation.3
Background	Chemokine (C-C motif) ligand 25 (CCL25) is a small cytokine belonging to the CC chemokine family that is also known as TECK (Thymus-Expressed ChemoKine). CCL25 is believed to play a role in the development of T-cells.¹ It is chemotactic for thymocytes, macrophages, and dendritic cells. CCL25 is expressed in the small intestinal epithelium and plays an important role in mediating lymphocyte recruitment to this site.² CCL25 is also highly expressed in the thymus, where it binds to its receptor CCR9 on thymocytes promoting migration and activation.³
Other Applications Reported In Literature	IHC (NBF/Par.): This antibody should give satisfactory staining results when used at a concentration of 25 µg/ml. The recommended secondary antibody for IHC is PN:R1215. For chromogenic detection with high signal and low background use PN:D100 or PN:K107.
PubMed	CCL25
Manufacturer - Research Area	Chemokine
Manufacturer - Specificity	Rat Anti-Mouse CCL25 (Clone 89827) recognizes an epitope on Mouse CCL25. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype. This antibody shows less than 1% cross-reactivity with other chemokines teste
RRID	AB_2828489
Formulation	This monoclonal antibody has been 0.2 µm filtered and lyophilized from modified Dulbecco's phosphate buffered saline (1X PBS) pH 7.2 - 7.3 containing 5.0% w/v trehalose with no calcium, magnesium or preservatives present.
Endotoxin Level	< 0.1 EU/µg as determined by the LAL method
Immunogen	Purified Recombinant Mouse CCL25 (> 98%)
Additional Information	Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.
Keywords	Monoclonal Antibody, Chemokine (C-C Motif) Ligand 25, SCYA25, TECK, Ckb15, 89827, CCL25, Mouse, Anti-Mouse CCL25, C-C motif chemokine 25, CCL25, chemokine (C-C motif) ligand 25, Chemokine TECK, Ck beta-15, Ckb15, SCYA25TECKvar, small inducible cytokine subfamily A (Cys-Cys), member 25, Small-inducible cytokine A25, TECK, TECKMGC150327, thymus expressed chemokine, Thymus-expressed chemokine

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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LEIN-C1429-500ug-safety-datasheet.pdf