Anti-Human CCR2 - APC - 25 tests

Quality Tested by Leinco Flow Cytometry: This conjugate has been pre-diluted to use approximately 10 µl per test when staining cells for flow cytometry. A typical test sample constitutes approximately 50 µl of packed whole blood or 1 x 10⁶ continuous passage or activated cell cultures that have been centrifuged at 500 X g for five minutes and resuspended in 200-400 µl of 1X PBS.

CCR2

Next Day 2 - 8°C

CCR2, short for chemokine (C-C motif) receptor 2, is a chemokine receptor. CCR2 has also recently been designated CD192 (cluster of differentiation 192). This gene encodes two isoforms of a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The receptors encoded by this gene mediate agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This gene is located in the chemokine receptor gene cluster region. Two alternatively spliced transcript variants are expressed by the gene.

CCR2

Mouse Anti-Human CCR2 (Clone 48607) recognizes an epitope on Human CCR2. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.

This monoclonal antibody is conjugated to allophycocyanin (APC) and formulated in modified Dulbecco's phosphate buffered saline (1X PBS) pH 7.2 - 7.3 containing 0.1% sodium azide as a preservative.

Monoclonal Antibody, CCR2, CD192, 48607, Human, Anti-Human CCR2-Allophycocyanin-(APC)