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Anti-Mouse CD4 [GK1.5] – DyLight® 488

Anti-Mouse CD4 [GK1.5] – DyLight® 488

Item no.	LEIN-C1636-100ug
Manufacturer	Leinco Technologies
Amount	100 ug
Quantity options	100 ug 50 ug
Category	Oncology Neuroscience Aging & Neurological Disorders Antibodies By Cell Type Carcinoma Hematology Leukemia Lymphoma Flow Cytometry Immunohistochemistry Immunocytochemistry Primary Antibodies Immunochemistry
Type	Antibody Monoclonal
Applications	FC, IHC, ICC
Clone	GK1.5
Specific against	Mouse (Murine, Mus musculus)
Host	Rat
Citations	1. Hendrickson WA et al. (1994) Structure 2: 59
NCBI	12504
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Shipping Condition	Cool pack
Available
Manufacturer - Applications	FC, ICC, IHC FF
Manufacturer - Category	Primary Monoclonal Antibodies>Surfacetag Mouse CD Markers
Manufacturer - Targets	CD4
Country of Origin	USA
Shipping Temperature	Next Day 2 - 8°C
Storage Conditions	This DyLight® 488 conjugate is stable when stored at 2-8°C. Do not freeze.
Product Description	CD4 (cluster of differentiation 4) is a glycoprotein expressed on the surface of T helper cells, regulatory T cells, monocytes, macrophages, and dendritic cells. CD4 interacts with class II molecules of the major histocompatibility complex (MHC) enhancing the signal for T-cell activation.1
Background	CD4 (cluster of differentiation 4) is a glycoprotein expressed on the surface of T helper cells, regulatory T cells, monocytes, macrophages, and dendritic cells. CD4 interacts with class II molecules of the major histocompatibility complex (MHC) enhancing the signal for T-cell activation.¹
Other Applications Reported In Literature	IHC-FF ICC
PubMed	CD4
Excitation Laser	Blue Laser (493 nm)
Ligand/Receptor	MHC class II molecule
Manufacturer - Research Area	Immunology
Manufacturer - Specificity	Rat Anti-Mouse CD4 (Clone GK1.5) recognizes an epitope on Mouse CD4. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
RRID	AB_2828691
Concentration	0.2 mg/ml
Formulation	This DyLight® 488 conjugate is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative.
Antigen Distribution	The L3T4 antigen is expressed by the helper/inducer subset of mouse T-cells. The antigen is present on approximately 80% of thymocytes, 20% of spleen cells and 60% of lymph node cells. The expression of L3T4 correlates with class II MHC antigen reactivity on cloned T-cell lines.
Additional Information	Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.
Keywords	Monoclonal Antibody, CD4, CD4mut, L3T4, Ly-4, CD4 Antigen, GK1.5, Mouse CD4, Clone GK1.5, Flow Cytometry

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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LEIN-C1636-100ug-safety-datasheet.pdf