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Anti-Human CD22 - Purified - 50 µg

Anti-Human CD22 - Purified - 50 µg

Item no.	LEIN-C179-50ug
Manufacturer	Leinco Technologies
Amount	50 ug
Quantity options	100 ug 200 ug 50 ug
Category	Oncology Antibodies By Cell Type Hematology Leukemia Lymphoma Cell Biology Cell Movement Cell Adhesion Flow Cytometry Immunohistochemistry Primary Antibodies
Type	Antibody Monoclonal
Applications	FC, IHC
Clone	RFB-4
Specific against	Human (Homo sapiens)
Host	Mouse
NCBI	933
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Shipping Condition	Room temperature
Available
Manufacturer - Applications	FC, IHC FF
Manufacturer - Category	Primary Monoclonal Antibodies>SurfaceTag Human CD Markers
Manufacturer - Targets	CD22
Country of Origin	USA
Shipping Temperature	Next Day Ambient
Storage Conditions	This purified antibody is stable when stored at 2-8°C. Do not freeze.
Product Description	Cluster of differentiation 22 also known as CD22 is a B-cell-restricted transmembrane protein, which acts as a negative regulator of B-cell signalling. CD22 also has lectin-like adhesive properties.2 CD22 is a good target to shorten the time required for Ab production, thereby augmenting host defense against acute infectious diseases as "universal vaccination."3
Background	Cluster of differentiation 22 also known as CD22 is a B-cell-restricted transmembrane protein, which acts as a negative regulator of B-cell signalling. CD22 also has lectin-like adhesive properties.² CD22 is a good target to shorten the time required for Ab production, thereby augmenting host defense against acute infectious diseases as "universal vaccination."³
Other Applications Reported In Literature	IHC (Frozen)
PubMed	CD22
Ligand/Receptor	CD45RO, CD75
Manufacturer - Research Area	Cell Adhesion, Cell Biology, Immunology
Manufacturer - Specificity	Mouse Anti-Human CD22 (Clone RFB-4) recognizes Human CD22. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype. Specificity: Anti-Human CD22 recognizes the (Mr 135 kDa) cytoplasmic antigen of all B-lymphocytes. The CD22 antigen is only expressed on the cell surface of mature B-lymphocytes.
RRID	AB_2828857
Concentration	0.5 mg/ml
Formulation	This purified antibody is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative.
Antigen Distribution	The CD22 antigen is expressed on >90% of peripheral blood B-cells.2 This antigen is not present on T-cells, monocytes or macrophages. CD22 is expressed on most peripheral B-cell lymphomas and leukemias including hairy cell leukemia, but not on the immature bone marrow type of leukemia.
Additional Information	Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.
Keywords	Monoclonal Antibody, Cluster of Differentiation 22, BL-CAM, MGC130020, SIGLEC2, RFB-4, CD22, Human CD22, Anti-Human CD22 Purified

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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LEIN-C179-50ug-safety-datasheet.pdf