Anti-Mouse CD252 (OX40L) [Clone RM134L] – Biotin - 500 µg

Quality Tested by Leinco For flow cytometric staining, the suggested use of this reagent is ≤1.0 µg per million cells in 100 µl volume. Each lot of this antibody is quality control tested

CD252

Next Day 2 - 8°C

CD252 is a 35 kD member of the TNF superfamily and is the ligand for OX-40, which is primarily found on activated T cells. The CD252/OX-40 pair contributes to B-cell and T-cell interaction during the immune response. Both proliferative and IL-2 production responses of activated T cells are enhanced via OX-40 antigen stimulation, while proliferation and Ig secretion by activated B cells is enhanced via CD252 stimulation. Hence, because both T cells and B cells are activated in cross-linking, the CD252/OX-40 pair is considered reciprocally costimulatory.

B-cell/T-cell interaction, costimulation

CD252

Costimulatory Molecules, Immunology

AB_2829429

This biotinylated antibody is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative.

Activated B cells, antigen presenting cells

Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.