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Anti-Mouse CD28 [Clone 37.51] — Purified - 500 µg

Anti-Mouse CD28 [Clone 37.51] — Purified - 500 µg

Item no.	LEIN-C243-500ug
Manufacturer	Leinco Technologies
Amount	500 ug
Quantity options	500 ug 50 ug
Category	Antibodies Flow Cytometry Immunohistochemistry Immunoprecipitation Western Blot Primary Antibodies
Type	Antibody Monoclonal
Applications	WB, FC, IP, IHC
Clone	37, 51
Specific against	Mouse (Murine, Mus musculus)
Host	Hamster - Syrian
NCBI	12487
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Shipping Condition	Room temperature
Available
Manufacturer - Applications	FC, IHC FF, IP, WB
Manufacturer - Category	Primary Monoclonal Antibodies>Immune Checkpoints\|Primary Monoclonal Antibodies>Surfacetag Mouse CD Markers
Manufacturer - Targets	CD28
Country of Origin	USA
Shipping Temperature	Next Day Ambient
Storage Conditions	This purified antibody is stable when stored at 2-8°C. Do not freeze.
Product Description	CD28 is a 44 kD glycoprotein and a member of the Ig superfamily. In its capacity as a costimulatory receptor, CD28 produces co-stimulatory signals necessary for T cell activation and survival. CD28 is the only B7 receptor constitutively expressed on naive T cells. Without having this CD28/B7 interaction, T cells will fail to respond to their specific antigen when coming in contact with an MHC/antigen complex and thus, are said to be anergic.
Background	CD28 is a 44 kD glycoprotein and a member of the Ig superfamily. In its capacity as a costimulatory receptor, CD28 produces co-stimulatory signals necessary for T cell activation and survival. CD28 is the only B7 receptor constitutively expressed on naive T cells. Without having this CD28/B7 interaction, T cells will fail to respond to their specific antigen when coming in contact with an MHC/antigen complex and thus, are said to be anergic.
Other Applications Reported In Literature	IHC (Frozen) B Cosim IP
PubMed	CD28
Ligand/Receptor	CD80 (B7-1), CD86 (B7-2)
Manufacturer - Research Area	Costimulatory Molecules, Immunology
Manufacturer - Specificity	Clone 37.51 recognizes an epitope on mouse CD28.
RRID	AB_2829526
Concentration	0.5 mg/ml
Formulation	This purified antibody is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative.
Antigen Distribution	CD28 is expressed on thymocytes, CD4+, CD8+ peripheral T cells, NK cells.
Additional Information	Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.
Keywords	CD28 antigen (Tp44), CD28 antigen, CD28 molecule, CD28, MGC138290, T-cell-specific surface glycoprotein CD28, Tp44, anti CD28, Cluster of Differentiation 28, MGC138290, Tp44, 37407, CD28, mouse, Anti-mouse CD28, anti mouse CD28, T44

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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LEIN-C243-500ug-safety-datasheet.pdf