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Anti-Mouse CTLA-4 (CD152) [Clone UC10-4F10-11] — PE - 100 µg

Anti-Mouse CTLA-4 (CD152) [Clone UC10-4F10-11] — PE - 100 µg

Item no.	LEIN-C2445-100ug
Manufacturer	Leinco Technologies
Amount	100 ug
Quantity options	100 ug 50 ug
Category	Antibodies Flow Cytometry Primary Antibodies
Type	Antibody Monoclonal
Applications	FC
Clone	UC10-4F10-11
Specific against	Mouse (Murine, Mus musculus)
Host	Hamster - Armenian
NCBI	12477
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Shipping Condition	Cool pack
Available
Manufacturer - Category	Primary Monoclonal Antibodies>Immune Checkpoints\|Primary Monoclonal Antibodies>Surfacetag Mouse CD Markers
Manufacturer - Targets	CTLA-4
Country of Origin	USA
Shipping Temperature	Next Day 2 - 8°C
Storage Conditions	This R-phycoerythrin (R-PE) conjugate is stable when stored at 2-8°C. Do not freeze.
Product Description	CTLA-4 is a 33 kD member of the Ig superfamily similar to CD28 in amino acid sequence, structure, and genomic organization. CTLA-4 is a protein receptor that functions as an immune checkpoint and downregulates immune responses. It is involved in the development of protective immunity and thymocyte regulation, in addition to the induction and maintenance of immunological tolerance. CTLA-4 has therapeutic potential both as an agonist to reduce immune activity, and an antagonist to increase immune activity.
Background	CTLA-4 is a 33 kD member of the Ig superfamily similar to CD28 in amino acid sequence, structure, and genomic organization. CTLA-4 is a protein receptor that functions as an immune checkpoint and downregulates immune responses. It is involved in the development of protective immunity and thymocyte regulation, in addition to the induction and maintenance of immunological tolerance. CTLA-4 has therapeutic potential both as an agonist to reduce immune activity, and an antagonist to increase immune activity.
PubMed	CTLA-4
Excitation Laser	Blue Laser (488 nm) and/or Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Manufacturer - Research Area	Immunology
Manufacturer - Specificity	Clone UC10-4F10-11 recognizes an epitope on mouse CTLA-4.
RRID	AB_2829542
Concentration	0.2 mg/ml
Formulation	This R-phycoerythrin (R-PE) conjugate is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative.
Antigen Distribution	CTLA-4 is expressed on activated T and B lymphocytes.
Immunogen	Mouse CTLA-4 IgG2a Fusion
Additional Information	Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.
Keywords	CD152 antigen, CD152, CD152IDDM12, celiac disease 3, CELIAC3, CTLA4, CTLA-4, cytotoxic T-lymphocyte antigen 4, cytotoxic T-lymphocyte protein 4, Cytotoxic T-lymphocyte-associated antigen 4, cytotoxic T-lymphocyte-associated protein 4, cytotoxic T-lymphocyte-associated serine esterase-4, GRD4, GSE, ICOS, ligand and transmembrane spliced cytotoxic T lymphocyte associated antigen 4, Cytotoxic T-lymphocyte-associated Molecule 4, Monoclonal Antibody, Cytotoxic T-Lymphocyte Antigen 4, CD152, CTLA4, 9H10, CTLA-4, Human CTLA-4, Anti-Human CD152, CTLA4, Human CTLA4, Human CTLA 4, Human CD152, Clone 9H10, 9H10 Antibody, B71, B71, Monoclonal Antibody, B7-1, Anti-Spec B7-1, Anti-B7-1, Clone 37711, Clone 111114, Clone 16-10A1 111114, 16-10A1, 37711, B7-2, B72, Anti-B7-2, Anti-B72, Clone GL1, GL1, Clone 3730, 3730, Clone 37407, Clone 37.5, 37407, 37.5, Anti CTLA-4, Anti CTLA4, Anti-ctla4, Anti-Ctla-4

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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LEIN-C2445-100ug-safety-datasheet.pdf