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Anti-Human Dtk (Clone 96201) - 500 µg

Anti-Human Dtk (Clone 96201) - 500 µg

Item no.	LEIN-D354-500ug
Manufacturer	Leinco Technologies
Amount	500 ug
Quantity options	100 ug 25 ug 500 ug
Category	Antibodies Flow Cytometry Immunohistochemistry ELISA Primary Antibodies Immunostaining
Type	Antibody Monoclonal
Applications	FC, IHC, ELISA
Clone	96201
Specific against	Human (Homo sapiens)
Host	Mouse
Citations	1. Crosier, KE.et al.(1996)Exp Hematol24:318 2. Crosier, PS.et al.(1994)Growth Factors11:137
NCBI	7301
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Shipping Condition	Room temperature
Available
Manufacturer - Applications	ELISA Cap, FC, IHC FFPE
Manufacturer - Category	Primary Monoclonal Antibodies>Growth Factors and Cytokines
Manufacturer - Targets	Dtk
Country of Origin	USA
Shipping Temperature	Next Day Ambient
Storage Conditions	The lyophilized antibody can be stored desiccated at -20°C to -70°C for up to twelve months. The reconstituted antibody can be stored for at least four weeks at 2-8°C. For long-term storage of the reconstituted antibody, aseptically aliquot into working volumes and store at -20°C to -70°C in a manual defrost freezer. Avoid repeated freeze thaw cycles. No detectable loss of activity was observed after six months.
Product Description	Dtk belongs to a recently recognized subfamily of receptor tyrosine kinases that also includes Ufo (Axl/Ark) and Mer (Eyk). Ligands for Dtk and Ufo have been identified as protein S and the related molecule Gas6, respectively. Dtk is likely to be involved in the regulation of hematopoiesis, particularly during the embryonic stages of blood cell development. 1 DTK is also abundantly expressed in adult kidney, testis, and ovary. 2
Background	Dtk belongs to a recently recognized subfamily of receptor tyrosine kinases that also includes Ufo (Axl/Ark) and Mer (Eyk). Ligands for Dtk and Ufo have been identified as protein S and the related molecule Gas6, respectively. Dtk is likely to be involved in the regulation of hematopoiesis, particularly during the embryonic stages of blood cell development. ¹ DTK is also abundantly expressed in adult kidney, testis, and ovary. ²
Other Applications Reported In Literature	IHC (NBF/Par.): This antibody should give satisfactory staining results when used at a concentration of 8 µg/ml. The recommended secondary antibody for IHC is PN:M114. For chromogenic detection with high signal and low background use PN:D100 or PN:K107.
PubMed	Dtk
Manufacturer - Specificity	Mouse Anti-Human Developmental Receptor Tyrosine Kinase (Dtk) (Clone 96201) recognizes an epitope on Human Dtk. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
RRID	AB_2829934
Formulation	This monoclonal antibody has been 0.2 µm filtered and lyophilized from modified Dulbecco's phosphate buffered saline (1X PBS) pH 7.2 - 7.3 containing 5.0% w/v trehalose with no calcium, magnesium or preservatives present.
Endotoxin Level	< 0.1 EU/µg as determined by the LAL method
Immunogen	Purified Recombinant Human Dtk (Accession # Q06418)
Additional Information	Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.
Keywords	Monoclonal Antibody, Developmental Receptor Tyrosine Kinase, 96201, Dtk, Human, Anti-Human Dtk, Brt, BYK, Dtk, EC 2.7.10, EC 2.7.10.1, FLJ16467, Rse, Sky, Tif, TYRO3 protein tyrosine kinase, Tyro3, Tyrosine-protein kinase byk, Tyrosine-protein kinase DTK, tyrosine-protein kinase receptor TYRO3, Tyrosine-protein kinase RSE, Tyrosine-protein kinase SKY

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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LEIN-D354-500ug-safety-datasheet.pdf