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Anti-Human Desmoglein-2 (Clone 141409) - 500 µg

Anti-Human Desmoglein-2 (Clone 141409) - 500 µg

Item no.	LEIN-D356-500ug
Manufacturer	Leinco Technologies
Amount	500 ug
Quantity options	25 ug 500 ug
Category	Antibodies Western Blot ELISA Immunocytochemistry Primary Antibodies Immunostaining Immunochemistry
Type	Antibody Monoclonal
Applications	WB, ICC, ELISA
Clone	141409
Specific against	Human (Homo sapiens)
Host	Mouse
Citations	1. Ozcelik, C. et al. (2008) Mol Genet Metab. 95(1-2):74-80.
NCBI	1829
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Shipping Condition	Room temperature
Available
Manufacturer - Applications	ELISA Indirect, ICC, WB
Manufacturer - Category	Primary Monoclonal Antibodies>Growth Factors and Cytokines
Manufacturer - Targets	Desmoglein-2
Country of Origin	USA
Shipping Temperature	Next Day Ambient
Storage Conditions	The lyophilized antibody can be stored desiccated at -20°C to -70°C for up to twelve months. The reconstituted antibody can be stored for at least four weeks at 2-8°C. For long-term storage of the reconstituted antibody, aseptically aliquot into working volumes and store at -20°C to -70°C in a manual defrost freezer. Avoid repeated freeze thaw cycles. No detectable loss of activity was observed after six months.
Product Description	Desmoglein 2, also known as DSG2, is a human gene. Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Desmoglein 2 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. It provides cellular adhesion and forces transduction by cell-to-cell anchorage. 1 It also plays a role in embryonic stem cell proliferation.
Background	Desmoglein 2, also known as DSG2, is a human gene. Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Desmoglein 2 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. It provides cellular adhesion and forces transduction by cell-to-cell anchorage. ¹ It also plays a role in embryonic stem cell proliferation.
Other Applications Reported In Literature	Immunocytochemistry: Suitable for use at concentration of 5-25 µg/mL.
PubMed	Desmoglein-2
Manufacturer - Specificity	Mouse Anti-Human Desmoglein-2 (DSG2) (Clone 141409) recognizes an epitope on Human DSG2. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
RRID	AB_2829936
Formulation	This monoclonal antibody has been 0.2 µm filtered and lyophilized from modified Dulbecco's phosphate buffered saline (1X PBS) pH 7.2 - 7.4 containing 5.0% w/v trehalose with no calcium, magnesium or preservatives present.
Immunogen	NS0-Derived Recombinant Human Desmoglein-2 (Accession # CAA81226)
Additional Information	Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.
Keywords	Monoclonal Antibody, Desmoglein-2, ARVC10, ARVD10, CDHF5, HDGC, MGC117034, MGC117036, MGC117037, 141409, DSG2, Human, Anti-Human Desmoglein-2, ARVC10, ARVD10, Cadherin family member 5, CDHF5, CDHF5MGC117034, CMD1BB, desmoglein 2, Desmoglein2, Desmoglein-2, DSG2, HDGC, MGC117036, MGC117037

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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LEIN-D356-500ug-safety-datasheet.pdf