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Anti-Human EDAR - 25 µg

Anti-Human EDAR - 25 µg

Item no.	LEIN-E228-25ug
Manufacturer	Leinco Technologies
Amount	25 ug
Quantity options	100 ug 25 ug
Category	Antibodies Western Blot Primary Antibodies
Type	Antibody Primary
Applications	WB, other
Specific against	Human (Homo sapiens)
Host	Caprine
Citations	1. Headon, DJ. et al. (2008)Hum Genet. 29:1405. 2. Tokunaga, K. et al. (2008)Hum Genet. 124:179.
NCBI	10913
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Shipping Condition	Room temperature
Available
Manufacturer - Applications	B, WB
Manufacturer - Category	Polyclonal Antibodies>Growth Factors & Cytokines
Manufacturer - Targets	EDAR
Country of Origin	USA
Shipping Temperature	Next Day Ambient
Storage Conditions	The lyophilized antigen affinity purified polyclonal antibody can be stored desiccated at -20°C to -70°C for twelve months from date of receipt. The reconstituted antibody can be stored for at least four weeks at 2-8°C. For long-term storage of the reconstituted antibody, aseptically aliquot into working volumes and store at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. No detectable loss of activity was observed after six months.
Product Description	Ectodysplasin A receptor, also known as EDAR is a cell surface receptor of the tumor necrosis factor receptor (TNFR) family involved in the development of hair follicles, teeth, and sweat glands. 1 EDAR is the genetic determinant of hair thickness as well as a strong contributor to hair fiber thickness variation among Asian populations. 2
Background	Ectodysplasin A receptor, also known as EDAR is a cell surface receptor of the tumor necrosis factor receptor (TNFR) family involved in the development of hair follicles, teeth, and sweat glands. ¹ EDAR is the genetic determinant of hair thickness as well as a strong contributor to hair fiber thickness variation among Asian populations. ²
Other Applications Reported In Literature	Blocking: Approximately 4-16 µg/ml of this antibody will block 50% of the binding of 10 µg/ml of human EDA/his to immobilized human EDAR/Fc chimera (100 µl of a 1 µg/ml solution was coated in each well) in a functional ELISA.
PubMed	EDAR
Manufacturer - Specificity	Goat Anti-Human Ectodysplasin A Receptor (EDAR) recognizes Human EDAR. This antigen affinity purified polyclonal antibody was purified using a proprietary chromatographic technique that includes covalently immobilizing the antigen proteins or peptides to agarose based beads. This purification method enhances specificity, reduces nonspecific binding of extraneous IgG and provides you with the most reliable reagent available for your early discovery research.
RRID	AB_2830000
Formulation	This antigen affinity purified polyclonal antibody has been 0.2 µm filtered and lyophilized from modified Dulbecco’s phosphate buffered saline (1X PBS) pH 7.2 – 7.3 containing 5.0% w/v trehalose with no calcium, magnesium, or preservatives present.
Endotoxin Level	< 0.1 EU/µg as determined by the LAL method
Immunogen	Purified Recombinant Human EDAR (> 98%)
Additional Information	Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.
Keywords	Polyclonal Antibody, Ectodysplasin A Receptor, DL, ED1R, ED3, ED5, EDA-A1R, EDA1R, EDA3, FLJ94390 , EDAR, Human EDAR, Anti-Human EDAR, Anhidrotic ectodysplasin receptor 1, DLED3, Ectodermal dysplasia receptor, ectodysplasin 1, anhidrotic receptor, ectodysplasin A receptor, Ectodysplasin-A receptor, ED1R, ED5, EDA1R, EDA3EDA-A1 receptor, EDA-A1R, EDAR, FLJ94390, HRM1, mouse, homolog of, tumor necrosis factor receptor superfamily member EDAR

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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LEIN-E228-25ug-safety-datasheet.pdf