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Anti-Mouse Gas6 - 25 µg

Anti-Mouse Gas6 - 25 µg

Item no.	LEIN-G659-25ug
Manufacturer	Leinco Technologies
Amount	25 ug
Quantity options	100 ug 25 ug
Category	Antibodies Immunohistochemistry ELISA Primary Antibodies Immunostaining
Type	Antibody Primary
Applications	IHC, ELISA
Specific against	Mouse (Murine, Mus musculus)
Host	Caprine
Citations	1. Suda, T. et al. (1998) Stem Cells 16: 229 2. Schneider, C. et al. (2001) Mol Cell Biol. 21: 902 3. Aglietta, M. et al. (1997) Exp Hematol. 25: 1219 4. Angelillo-Scherrer, A. et al. (2005) J Clin Invest. 115(2):237-46.
NCBI	14456
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Shipping Condition	Room temperature
Available
Manufacturer - Applications	ELISA Cap, IHC
Manufacturer - Category	Polyclonal Antibodies>Growth Factors & Cytokines
Manufacturer - Targets	Gas6
Country of Origin	USA
Shipping Temperature	Next Day Ambient
Storage Conditions	The lyophilized antigen affinity purified polyclonal antibody can be stored desiccated at -20°C to -70°C for twelve months from date of receipt. The reconstituted antibody can be stored for at least four weeks at 2-8°C. For long-term storage of the reconstituted antibody, aseptically aliquot into working volumes and store at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. No detectable loss of activity was observed after six months.
Product Description	Growth arrest-specific 6, also known as GAS6 is a growth factor1 that serves as a ligand for members of the Axl subfamily of receptor protein-tyrosine kinases.2 GAS6 is expressed in hematopoietic tissue.3 GAS6 function as a direct regulator of osteoclastic function; they give an insight into the role of these vitamin K-dependent ligands in bone resorption in vivo.2 GAS6 has a potential therapeutic target to minimize graft-versus-host disease (GVHD).4
Background	Growth arrest-specific 6, also known as GAS6 is a growth factor¹ that serves as a ligand for members of the Axl subfamily of receptor protein-tyrosine kinases.² GAS6 is expressed in hematopoietic tissue.³ GAS6 function as a direct regulator of osteoclastic function; they give an insight into the role of these vitamin K-dependent ligands in bone resorption in vivo.² GAS6 has a potential therapeutic target to minimize graft-versus-host disease (GVHD).⁴
Other Applications Reported In Literature	Immunohistochemistry: Suitable for use at concentration of 1-15 µg/mL.
PubMed	Gas6
Manufacturer - Specificity	Goat Anti-Mouse Growth Arrest-Specific Gene 6 (Gas6) recognizes Mouse Gas6. This antigen affinity purified polyclonal antibody was purified using a proprietary chromatographic technique that includes covalently immobilizing the antigen proteins or peptides to agarose based beads. This purification method enhances specificity, reduces nonspecific binding of extraneous IgG and provides you with the most reliable reagent available for your early discovery research.
RRID	AB_2830249
Formulation	This antigen affinity purified polyclonal antibody has been 0.2 µm filtered and lyophilized from modified Dulbecco’s phosphate buffered saline (1X PBS) pH 7.2 – 7.3 containing 5.0% w/v trehalose with no calcium, magnesium, or preservatives present.
Endotoxin Level	< 0.1 EU/µg as determined by the LAL method
Immunogen	Purified Recombinant Mouse Gas6 (> 98%)
Additional Information	Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.
Keywords	Polyclonal Antibody, Growth Arrest-Specific Gene 6, AXLLG, AXSF, DKFZp666G247, FLJ34709, Gas6, Mouse Gas6 , Anti-Mouse Gas6, AXLLG, AXLLGAXL stimulatory factor, AXSFAXL receptor tyrosine kinase ligand, DKFZp666G247, FLJ34709, Gas6, GAS-6, growth arrest-specific 6, growth arrest-specific protein 6

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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LEIN-G659-25ug-safety-datasheet.pdf