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Anti-Mouse/Human IL-5 - Purified - 500 µg

Anti-Mouse/Human IL-5 - Purified - 500 µg

Item no.	LEIN-I-1038-500ug
Manufacturer	Leinco Technologies
Amount	500 ug
Quantity options	500 ug 50 ug
Category	Antibodies Immunohistochemistry Western Blot ELISA Primary Antibodies Immunostaining
Type	Antibody Monoclonal
Applications	WB, IHC, ELISA
Clone	TRFK5
Specific against	Mouse (Murine, Mus musculus)
Host	Rat
NCBI	16191 3567
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Shipping Condition	Cool pack
Available
Manufacturer - Applications	ELISA Cap, IHC FF, IHC FFPE, WB
Manufacturer - Category	Primary Monoclonal Antibodies>Growth Factors and Cytokines
Manufacturer - Targets	IL-5
Country of Origin	USA
Shipping Temperature	Next Day 2 - 8°C
Storage Conditions	This Purified conjugate is stable when stored at 2-8°C. Do not freeze.
Product Description	IL-5 is a 26 kD TH2 cytokine and a homodimeric glycoprotein that is part of the hematopoietic family. IL-5 stimulates B cell growth as well as increases Ig secretion. It is the main factor that promotes the terminal differentiation of eosinophil progenitors and enhances the effector capacity of mature eosinophils. IL-5 is a major regulator of eosinophil accumulation in tissues. In fact, in Hodgkin lymphoma, the characteristically observed eosinophilia is suspected to result from an increased production of IL-5. IL-5 may also be the cause of several allergic diseases including asthma, where it is thought that eosinophils have a significant role in the disease pathology. There are several mAbs currently in use that target IL-5 for the treatment of severe eosinophilic asthma.
Background	IL-5 is a 26 kD TH2 cytokine and a homodimeric glycoprotein that is part of the hematopoietic family. IL-5 stimulates B cell growth as well as increases Ig secretion. It is the main factor that promotes the terminal differentiation of eosinophil progenitors and enhances the effector capacity of mature eosinophils. IL-5 is a major regulator of eosinophil accumulation in tissues. In fact, in Hodgkin lymphoma, the characteristically observed eosinophilia is suspected to result from an increased production of IL-5. IL-5 may also be the cause of several allergic diseases including asthma, where it is thought that eosinophils have a significant role in the disease pathology. There are several mAbs currently in use that target IL-5 for the treatment of severe eosinophilic asthma.
Other Applications Reported In Literature	Additional reported applications (for the relevant formats) include: Neutralization Flow Cytometry Western Blotting IHC-FFPE IHC-FF
PubMed	IL-5
Manufacturer - Specificity	Clone TRFK5 recognizes mouse/human IL-5.
RRID	AB_2830369
Concentration	0.5 mg/ml
Formulation	This Purified conjugate is formulated in 0.01 M phosphate buffered saline (PBS) pH 7.4, 150 mM NaCl, 1% BSA and 0.09% sodium azide as a preservative.
Product Preparation	This monoclonal antibody was purified by affinity chromatography.
Immunogen	Partially-purified T cell clone supernatant
Additional Information	Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.
Keywords	Monoclonal Antibody, Interleukin-5, EDF, BCDFII, TRF, TRFK5, IL-5, Mouse, Anti-Mouse/Human IL-5 - Purified

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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LEIN-I-1038-500ug-safety-datasheet.pdf