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Anti-Mouse IFN-γ (Clone XMG1.2) - DyLight® 650

Anti-Mouse IFN-γ (Clone XMG1.2) - DyLight® 650

Item no.	LEIN-I-1128-200ug
Manufacturer	Leinco Technologies
Amount	200 ug
Quantity options	100 ug 200 ug 50 ug
Category	Antibodies Primary Antibodies
Type	Antibody Monoclonal
Clone	XMG1.2
Specific against	Mouse (Murine, Mus musculus)
Host	Rat
NCBI	15978
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Shipping Condition	Cool pack
Available
Manufacturer - Category	Primary Monoclonal Antibodies>Growth Factors and Cytokines
Manufacturer - Targets	IFN-γ
Country of Origin	USA
Shipping Temperature	Next Day 2-8°C
Storage Conditions	This DyLight® 650 conjugate is stable when stored at 2-8°C. Do not freeze.
Product Description	Interferon-gamma (IFN-γ) or type II interferon is a dimerized soluble cytokine that is the only member of the type II class of interferons.1 It is a cytokine critical for innate and adaptive immunity against viral and intracellular bacterial infections and for tumor control. IFNG is produced predominantly by natural killer (NK) and natural killer T (NKT) cells as part of the innate immune response, and by CD4 and CD8 cytotoxic T lymphocyte (CTL) effector T cells once antigen-specific immunity develops.2 IFN-γ has antiviral, immunoregulatory, and anti-tumour properties.3
Background	Interferon-gamma (IFN-γ) or type II interferon is a dimerized soluble cytokine that is the only member of the type II class of interferons.¹ It is a cytokine critical for innate and adaptive immunity against viral and intracellular bacterial infections and for tumor control. IFNG is produced predominantly by natural killer (NK) and natural killer T (NKT) cells as part of the innate immune response, and by CD4 and CD8 cytotoxic T lymphocyte (CTL) effector T cells once antigen-specific immunity develops.² IFN-γ has antiviral, immunoregulatory, and anti-tumour properties.³
Other Applications Reported In Literature	ICFC The suggested concentration for clone XMG1.2 conjugated antibody for staining cells in Intracellular Immunofluorescent flow cytometry is ≤ .25 μg per 10⁶ cells in a volume of 100 μl or 100μl of whole blood. Titration of the reagent is recommended for optimal performance for each application.
PubMed	IFN-γ
Excitation Laser	Red Laser (652 nm)
Manufacturer - Research Area	Cell Biology, Immunology, Neuroinflammation, Neuroscience
Manufacturer - Specificity	Rat Anti-Mouse Interferon Gamma (IFN-γ) (Clone XMG1.2) recognizes an epitope on Mouse IFN-γ. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
RRID	AB_2830465
Concentration	0.2 mg/ml
Formulation	This DyLight® 650 conjugate is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative.
Immunogen	Purified Recombinant Mouse IFN-γ (> 98%)
Additional Information	Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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LEIN-I-1128-200ug-safety-datasheet.pdf